Anti-COX1 / Cyclooxygenase 1 antibody (ab84602)

Overview

  • Product name
    Anti-COX1 / Cyclooxygenase 1 antibody
    See all COX1 / Cyclooxygenase 1 primary antibodies
  • Description
    Rabbit polyclonal to COX1 / Cyclooxygenase 1
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH derived from within residues 550 to the C-terminus of Human COX1/ Cyclooxygenase 1.

    (Peptide available as ab93495.)

  • Positive control
    • This antibody gave a positive signal in the following human whole cell lysates: A431; HUVEC.

Properties

Applications

Our Abpromise guarantee covers the use of ab84602 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notes
    WB: Use at a concentration of 1 µg/ml. Detects a band of approximately 73 kDa (predicted molecular weight: 68 kDa).
    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      May play an important role in regulating or promoting cell proliferation in some normal and neoplastically transformed cells.
    • Pathway
      Lipid metabolism; prostaglandin biosynthesis.
    • Sequence similarities
      Belongs to the prostaglandin G/H synthase family.
      Contains 1 EGF-like domain.
    • Cellular localization
      Microsome membrane. Endoplasmic reticulum membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • COX 1 antibody
      • COX 3 antibody
      • COX-1 antibody
      • COX1 antibody
      • Cox3 antibody
      • Cyclooxygenase 1 antibody
      • Cyclooxygenase 3, included antibody
      • Cyclooxygenase-1 antibody
      • EC 1.14.99.1 antibody
      • Partial COX1 proteins, included antibody
      • PCOX1 antibody
      • PGG/HS antibody
      • PGH synthase 1 antibody
      • PGH1_HUMAN antibody
      • PGHS-1 antibody
      • PGHS1 antibody
      • PHS 1 antibody
      • PHS1 antibody
      • Prostaglandin G/H synthase 1 antibody
      • Prostaglandin H2 synthase 1 antibody
      • Prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) antibody
      • Prostaglandin-endoperoxide synthase 1 antibody
      • PTGHS antibody
      • PTGS1 antibody
      see all

    Images

    • All lanes : Anti-COX1 / Cyclooxygenase 1 antibody (ab84602) at 1 µg/ml

      Lane 1 : A431 (Human epithelial carcinoma cell line) Whole Cell Lysate
      Lane 2 : HUVEC (Human Umbilical Vein Endothelial Cell) Whole Cell Lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution
      Developed using the ECL technique

      Performed under reducing conditions.

      Predicted band size : 68 kDa
      Observed band size : 71,73 kDa (why is the actual band size different from the predicted?)
      Additional bands at : 55 kDa. We are unsure as to the identity of these extra bands.

      Exposure time : 2 minutes

    References

    ab84602 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    Thank you for your reply.

    Indeed, the other antibodies mentioned are only tested for WB so far, however, they are the antibodies against these targets that have the highest probability to cross-react with hamster due to sequence similarity o...

    Read More

    Thank you very much for contacting us.

    I am happy to let you know that we have the following antibodies available:

    COX-2: ab102005: Click here (or use the following: http://www.abcam.com/index.html?datasheet=102005).
    COX-1: a...

    Read More

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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