![Sandwich ELISA - COX2 / Cyclooxygenase 2 antibody [AS66] (ab90345) image](#COX2-Cyclooxygenase-2-Primary-antibodies-ab90345-5.jpg)
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Product name
Anti-COX2 / Cyclooxygenase 2 antibody [AS66]
See all COX2 / Cyclooxygenase 2 products (19) ...
Description
Mouse monoclonal [AS66] to COX2 / Cyclooxygenase 2
Tested applications
WB, ELISA, Flow Cyt, Sandwich ELISAmore details
Cross reactivity
Reacts with
Human
Immunogen
Recombinant Human COX2 / Cyclooxygenase 2 protein.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer
Preservative: 0.05% Sodium Azide
Constituents: PBS
Concentration
Concentration information loading...
Purification notes
Purified by 0.2 µm sterile filter
Clonality
Monoclonal
Clone number
AS66
Isotype
IgG1
Light chain type
kappa
Research areas
Metabolism >> Types of disease >> Heart disease
Metabolism >> Types of disease >> Cancer
Metabolism >> Pathways and Processes >> Endocrine metabolism >> Hormone biosynthesis
Metabolism >> Pathways and Processes >> Metabolic signaling pathways >> Lipid and lipoprotein metabolism >> Lipoprotein metabolism
Metabolism >> Pathways and Processes >> Metabolic signaling pathways >> Lipid and lipoprotein metabolism >> Cholesterol Metabolism
Cancer >> Cancer Metabolism >> Metabolic signaling pathway >> Hormone biosynthesis
Cardiovascular >> Atherosclerosis >> Lipoprotein metabolism
Cancer >> Tumor biomarkers >> Other
Signal Transduction >> Signaling Pathway >> Lipid Signaling >> Prostaglandins
Cardiovascular >> Lipids / Lipoproteins >> Lipid Metabolism >> Cholesterol Metabolism
Cardiovascular >> Blood >> Platelets
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Sandwich ELISA - COX2 / Cyclooxygenase 2 antibody [AS66] (ab90345)
![Sandwich ELISA - COX2 / Cyclooxygenase 2 antibody [AS66] (ab90345) image](/ps/datasheet/images/90/ab90345/COX2-Cyclooxygenase-2-Primary-antibodies-ab90345-5.jpg)
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Applications
Show applications key
Our Abpromise guarantee covers the use of ab90345 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 69 kDa.
ELISA: Use at an assay dependent dilution.
Flow Cyt: Use at an assay dependent dilution.
sELISA: Use a concentration of 1 µg/ml. Can be paired for Sandwich ELISA with Rabbit polyclonal to COX2 / Cyclooxygenase 2 (ab15191). For sandwich ELISA, use this antibody as Capture at 1µg/ml with ab15191 as Detection.
Target
Function
Mediates the formation of prostaglandins from arachidonate. May have a role as a major mediator of inflammation and/or a role for prostanoid signaling in activity-dependent plasticity.
Pathway
Lipid metabolism; prostaglandin biosynthesis.
Sequence similarities
Belongs to the prostaglandin G/H synthase family.
Contains 1 EGF-like domain.
Post-translational
modifications
S-nitrosylation by NOS2 (iNOS) activates enzme activity. S-nitrosylation may take place on different Cys residues in addition to Cys-561.
Cellular localization
Microsome membrane. Endoplasmic reticulum membrane.
Target information above from: UniProt accessionP35354
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- COX 2 antibody
- COX-2 antibody
- COX2 antibody
see all
Database links
- Entrez Gene: 5743 Human
- Omim: 600262 Human
- SwissProt: P35354 Human
- Unigene: 196384 Human
Anti-COX2 / Cyclooxygenase 2 antibody [AS66] images:
Sandwich ELISA - COX2 / Cyclooxygenase 2 antibody [AS66] (ab90345)
Standard Curve for COX2 / Cyclooxygenase 2 (Analyte: ab58868) dilution range 1pg/ml to 1ug/ml using Capture Antibody Mouse monoclonal [AS66] to COX2 / Cyclooxygenase 2 (ab90345) at 1ug/ml and Detector Antibody Rabbit polyclonal to COX2 / Cyclooxygenase 2 (ab15191) at 0.5ug/ml
Protocols
References for Anti-COX2 / Cyclooxygenase 2 antibody [AS66] (ab90345)
ab90345 has not yet been referenced specifically in any publications.
Publishing research using ab90345? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"