Anti-CPLX1 antibody (ab215066)
Key features and details
- Sheep polyclonal to CPLX1
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
Overview
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Product name
Anti-CPLX1 antibody
See all CPLX1 primary antibodies -
Description
Sheep polyclonal to CPLX1 -
Host species
Sheep -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse
Predicted to work with: Rat, Cow, Human, Cynomolgus monkey -
Immunogen
Recombinant full length protein corresponding to Human CPLX1 aa 1 to the C-terminus. (Derived from E.coli).
Database link: O14810 -
Positive control
- Mouse brain tissue lysate.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
Constituent: 100% PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Purification notes
The IgG fraction of immunized serum was purified by antigen affinity chromatography. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Isotype control
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Positive Controls
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Recombinant Protein
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Related Products
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab215066 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/1000 - 1/2000. Detects a band of approximately 18 kDa (predicted molecular weight: 15 kDa).
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Notes |
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WB
1/1000 - 1/2000. Detects a band of approximately 18 kDa (predicted molecular weight: 15 kDa). |
Target
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Function
Positively regulates a late step in synaptic vesicle exocytosis. Also involved in glucose-induced secretion of insulin by pancreatic beta-cells. -
Tissue specificity
Nervous system. In hippocampus and cerebellum, expressed mainly by inhibitory neurons. Overexpressed in substantia nigra from patients with Parkinson disease. -
Sequence similarities
Belongs to the complexin/synaphin family. -
Cellular localization
Cytoplasm > cytosol. Enriched at synaptic-releasing sites in mature neurons. - Information by UniProt
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Database links
- Entrez Gene: 768228 Cow
- Entrez Gene: 102114990 Cynomolgus monkey
- Entrez Gene: 10815 Human
- Entrez Gene: 12889 Mouse
- Entrez Gene: 64832 Rat
- Omim: 605032 Human
- SwissProt: Q0IIL7 Cow
- SwissProt: Q4R4N1 Cynomolgus monkey
see all -
Alternative names
- 921-S antibody
- complexin 1 antibody
- Complexin I antibody
see all
Images
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Anti-CPLX1 antibody (ab215066) at 1/1000 dilution + Mouse brain tissue lysate
Predicted band size: 15 kDa
Observed band size: 18 kDa why is the actual band size different from the predicted?
Datasheets and documents
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Datasheet download
References (0)
ab215066 has not yet been referenced specifically in any publications.