Overview

  • Product name
  • Description
    Rabbit polyclonal to CPSF2
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Dog, Turkey, Chimpanzee, Rhesus monkey, Gorilla, Xenopus tropicalis
  • Immunogen

    corresponding to a region within internal sequence amino acids 450-500 of Human CPSF2 (NP_059133.1)

  • Positive control
    • Human Anaplastic Thyroid Carcinoma, Human Breast Carcinoma, Human Linitis Plastica Stomach Cancer, Human Ovarian Carcinoma, Human Testicular Seminoma.

Properties

Applications

Our Abpromise guarantee covers the use of ab100807 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/500. Epitope exposure with citrate buffer will enhance staining.

Target

  • Relevance
    CPSF2 belongs to the RNA-metabolizing metallo-beta-lactamase-like family, CPSF2/YSH1 subfamily. It is a component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3 prime-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. A poly(A) tail is added to eukaryotic mRNA precursors after tightly coupled cleavage and polyadenylation reactions at their 3-prime ends.
  • Cellular localization
    Nuclear
  • Database links
  • Alternative names
    • Cleavage and polyadenylation specific factor 2 antibody
    • cleavage and polyadenylation specific factor 2, 100kDa antibody
    • Cleavage and polyadenylation specificity factor 100 kDa subunit antibody
    • Cleavage and polyadenylation specificity factor subunit 2 antibody
    • CPSF 100 kDa subunit antibody
    • CPSF 2 antibody
    • CPSF100 antibody
    • KIAA1367 antibody
    • zgc:92484 antibody
    see all

Images

  • ab100807, at 1/250 dilution, staining CPSF2 in Human ovarian carcinoma by immunohistochemistry.
  • ab100807, at 1/250 dilution, staining CPSF2 in Mouse teratoma by immunohistochemistry.

References

ab100807 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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