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MitoSciences (MS1071 )

CPT1A protein (His tag) (ab128569)

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Overview

  • Product nameCPT1A protein (His tag)See all CPT1A proteins and peptides ...
  • Protein descriptionRecombinant fragment corresponding to amino acids 489-773 of Human CPT1A with C terminal His tag; Predicted MWt 32 kDa excluding tag (UniProt P50416).
  • Uniprot accessionP50416
  • Molecular weight32kDa
  • Protein length285 amino acids
  • Expression hostE. coli

    • Properties

  • Purity> 80 % by SDS-PAGE
  • E.C. Number2.3.1.21
  • FormLiquid
  • Storage instructionsShipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
  • Storage bufferConstituents: 0.79% Tris HCl, 0.15% EDTA, 50% Glycerol, 0.88% Sodium chloride
  • Concentration information loading...
  • Sequence notesMSIDSLQLGY AEDGHCKGDI NPNIPYPTRL QWDIPGECQE VIETSLNTAN LLANDVDFHS FPFVAFGKGIIKKCRTSPDA FVQLALQLAH YKDMGKFCLT YEASMTRLFR EGRTETVRSC TTESCDFVRA MVDPAQTVEQRLKLFKLASE KHQHMYRLAM TGSGIDRHLF CLYVVSKYLA VESPFLKEVL SEPWRLSTSQ TPQQQVELFDLENNPEYVSS GGGFGPVADD GYGVSYILVG ENLINFHISS KFSCPETDSH RFGRHLKEAM TDIITLFGLS SNSKK
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab128569 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    SDS-PAGE SDS-PAGE: Use at an assay dependent concentration.
    WB WB: Use at an assay dependent concentration.
    ELISA ELISA: Use at an assay dependent concentration.
  • Application notesThis peptide can be used with studies using ab128568.

    • Protein info

    • Alternative names
        Carnitine O palmitoyltransferase 1 liver isoformCarnitine O palmitoyltransferase ICarnitine O palmitoyltransferase I liver isoform
        Carnitine O-palmitoyltransferase 1Carnitine O-palmitoyltransferase ICarnitine palmitoyltransferase 1ACarnitine palmitoyltransferase 1A (liver)Carnitine palmitoyltransferase ICarnitine palmitoyltransferase I liverCPT 1CPT ICPT1CPT1 LCPT1-LCpt1aCPT1A_HUMANCPTICPTI-LL CPT1liver isoform
      see all
  • Tissue specificityStrong expression in kidney and heart, and lower in liver and skeletal muscle.
  • PathwayLipid metabolism; fatty acid beta-oxidation.
  • Involvement in diseaseDefects in CPT1A are the cause of carnitine palmitoyltransferase 1A deficiency (CPT1AD) [MIM:255120]; also known as CPT-I deficiency or CPT1A deficiency. CPT1AD is a rare autosomal recessive metabolic disorder of long-chain fatty acid oxidation characterized by severe episodes of hypoketotic hypoglycemia usually occurring after fasting or illness. Onset is in infancy or early childhood.
  • Sequence similaritiesBelongs to the carnitine/choline acetyltransferase family.
  • Cellular localizationMitochondrion outer membrane.

    • Target information above from: UniProt accession P50416 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    CPT1A protein (His tag) images

    • SDS-PAGE - CPT1A protein (His tag) (ab128569)
      SDS-PAGE - CPT1A protein (His tag) (ab128569)
      Lane 1 : Marker
      Lane 2 : Partial Human Recombinant CPT1A protein 1 µg

      Gel
      10-20% acrylamide separation gel

      Predicted band size : 32 kDa
      Observed band size : 32 kDa

    References for CPT1A protein (His tag) (ab128569)

    ab128569 has not yet been referenced specifically in any publications.

    Publishing research using ab128569 ? Please let us know so that we can cite the reference in this datasheet

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