Overview

  • Product name
    CRT0066101 (mM/ml)
  • Description
    Potent and selective protein kinase D inhibitor. 1 ml water soluble pack.
  • Biological description
    Potent and selective protein kinase D inhibitor (IC50 values are 1, 2 and 2.5 nM at PKD1, PKD3 and PKD2, respectively). Reduces proliferation of pancreatic cancer cells. Orally active. Antitumor agent. Active in vivo and in vitro.

    Soluble in 1 ml water to give specified mM/ml concentration. Find out more.
  • Purity
    > 99%

Properties

  • Chemical name
    2-[4-[[(2R)-2-Aminobutyl]amino]pyrimidin-2-yl]-4-(1-methyl-1H-pyrazol-4-yl)phenol dihydrochloride
  • Molecular weight
    411.33
  • Chemical structure
    Chemical Structure
  • Molecular formula
    C18H22N6O.2HCl
  • Storage instructions
    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview
    Soluble in 1ml of water to give specified mM/ml concentration
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES
    Cl.Cl.Cn1cc(cn1)c3cc(c2nc(NC[C@H](N)CC)ccn2)c(O)cc3
  • Source

    Synthetic

  • Research areas

References

ab146740 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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