|
|
|
|
IHC-P - CSK antibody (ab54684)
(enlarge)
|
|
Western blot - CSK antibody (ab54684)
(enlarge)
|
|
|
|
|
Product Name
|
CSK antibody
|
| |
See all CSK antibodies (7)...
|
|
Product type
|
Primary antibodies
|
|
Description
|
Mouse monoclonal to CSK
|
|
Immunogen
|
Recombinant fragment: MSAIQAAWPS GTECIAKYNF HGTAEQDLPF CKGDVLTIVA VTKDPNWYKA KNKVGREGII PANYVQKREG VKAGTKLSLM PWFHGKITRE QAERLLYPPE , corresponding to amino acids 1-101 of Human CSK
BLAST 'MSAIQAAWPS GTECIAKYNF HGTAEQDLPF CKGDVLTIVA VTKDPNWYKA KNKVGREGII PANYVQKREG VKAGTKLSLM PWFHGKITRE QAERLLYPPE ' with  or 
|
|
Reacts with
(species key)
|
Hu
|
|
Tested applications
(see key)
|
IHC-P, WB
|
|
|
Abreviews
|
|
|
|
Application notes
(see key)
|
Recommended dilutions
WB: Use at a concentration of 1-5 µg/ml.
IHC-P: Use at a concentration of 1 µg/ml.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
|
|
Cellular localization
|
Cytoplasmic
|
|
Research areas
|
Signal Transduction >> Protein Phosphorylation >> Tyrosine Kinases >> Src Family
|
|
Relevance
|
C terminal Src kinase (CSK) is a non receptor protein tyrosine kinase. One of its major functions is to specifically phosphorylate a conserved C terminal tyrosine of Src family kinases thereby down regulating their kinase activity. CSK is expressed ubiquitously as a protein of approximately 50 KDa in cytosol, but a fraction distributes to lipid rafts due to interaction with the lipid raft associated protein PAG (CSK binding protein).
|
|
|
|
|
Database links
|
The links below go to external sites and will open in a new browser window |
|
Raised in
|
Mouse
|
|
Clonality
|
Monoclonal
|
|
Isotype
|
IgG1
|
|
Light chain type
|
kappa
|
|
Purity
|
Protein G purified
|
|
Storage buffer
|
Preservative: None
PBS, pH 7.2
|
|
Form
|
Liquid
|
|
Concentration
|
1.000 mg/ml
|
|
Storage instructions
|
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
|
| |
At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this CSK antibody is on this datasheet. But please do contact us if you would like any reassurance! |
 |
|
| |
CSK antibody images:
|
 IHC-P - CSK antibody (ab54684)
CSK antibody (ab54684) used in immunohistochemistry at 1ug/ml on formalin fixed and paraffin embedded human colon.
|
| |
Western blot - CSK antibody (ab54684)
Predicted band size : 51 kDa
CSK antibody (ab54684) at 1ug/lane + HL-60 cell lysate at 25ug/lane.
|
| |
| |
|
Search PubMed (MEDLINE) for references to CSK
|
| |
CSK antibody - more information
|
Customer reviews (feedback) regarding CSK antibody |
Customer FAQs regarding CSK antibody |
Protocols for CSK antibody |
Price and availability of products related to CSK antibody |
| |
CSK antibody - other tools:
|
Contact Abcam with a Technical Enquiry about CSK antibody |
| |
All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
Pricing information loading
