Anti-CTDSP2 antibody [2230C1a] (ab50621)
Key features and details
- Mouse monoclonal [2230C1a] to CTDSP2
- Suitable for: WB
- Reacts with: Recombinant fragment
- Isotype: IgG2b
Overview
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Product name
Anti-CTDSP2 antibody [2230C1a]
See all CTDSP2 primary antibodies -
Description
Mouse monoclonal [2230C1a] to CTDSP2 -
Host species
Mouse -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Recombinant fragment -
Immunogen
Recombinant fragment, corresponding to near the N terminal amino acids 21-124 of Human CTDSP2
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Positive control
- recombinant human CTDSP2 fragment
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.4
Preservative: 0.05% Sodium azide
Constituents: PBS, 1% BSA -
Concentration information loading...
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Purity
Protein G purified -
Purification notes
ab50621 was purified from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum. -
Clonality
Monoclonal -
Clone number
2230C1a -
Isotype
IgG2b -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab50621 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/100. Detects a band of approximately 35 kDa (predicted molecular weight: 31 kDa).
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Notes |
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WB
1/100. Detects a band of approximately 35 kDa (predicted molecular weight: 31 kDa). |
Target
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Function
Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas. -
Tissue specificity
Expression is restricted to non-neuronal tissues. Highest expression in pancreas and lowest in liver. -
Sequence similarities
Contains 1 FCP1 homology domain. -
Cellular localization
Nucleus. - Information by UniProt
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Alternative names
- Carboxy terminal domain RNA polymerase II polypeptide A small phosphatase 2 antibody
- Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 antibody
- conserved gene amplified in osteosarcoma 4 antibody
see all
Images
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Anti-CTDSP2 antibody [2230C1a] (ab50621) + recombinant CTDSP2 fragment
Predicted band size: 31 kDa
Observed band size: 35 kDa why is the actual band size different from the predicted?
Datasheets and documents
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Datasheet download
References (0)
ab50621 has not yet been referenced specifically in any publications.