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Anti-CTGF antibody (ab6992)

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Publishing research using ab6992? Please let us know so that we can cite the reference in this datasheet

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ab6992 has been referenced in 43 publications.

  1. Candido R et al. A breaker of advanced glycation end products attenuates diabetes-induced myocardial structural changes. Circ Res 92:785-92 (2003). PubMed: 12623881
  2. Razzaque MS et al. Role of connective tissue growth factor in the pathogenesis of conjunctival scarring in ocular cicatricial pemphigoid. Invest Ophthalmol Vis Sci 44:1998-2003 (2003). PubMed: 12714635
  3. Haafiz A et al. Relationship between hepatic CTGF expression and routine blood tests at the time of liver transplantation for biliary atresia: hope or hype for a biomarker of hepatic fibrosis. Clin Exp Gastroenterol 4:49-54 (2011). IHC-P; Human. PubMed: 21694872
  4. Yang L et al. Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury. Nat Med 16:535-43, 1p following 143 (2010). WB; Mouse. PubMed: 20436483
  5. Shi-wen X et al. Rosiglitazone alleviates the persistent fibrotic phenotype of lesional skin scleroderma fibroblasts. Rheumatology (Oxford) 49:259-63 (2010). WB; Human. PubMed: 20007285
  6. Ibba-Manneschi L et al. Severe fibrotic changes and altered expression of angiogenic factors in maternal scleroderma: placental findings. Ann Rheum Dis 69:458-61 (2010). IHC-P; Human. PubMed: 19336420
  7. Qiu Z et al. c-Abl tyrosine kinase regulates cardiac growth and development. Proc Natl Acad Sci U S A 107:1136-41 (2010). WB; Mouse. PubMed: 20080568
  8. Liu S et al. Connective tissue growth factor is induced in bleomycin-induced skin scleroderma. J Cell Commun Signal : (2009). PubMed: 19916059
  9. Gaultier A et al. Low-density lipoprotein receptor-related protein 1 is an essential receptor for myelin phagocytosis. J Cell Sci 122:1155-62 (2009). IHC-Fr; Human. PubMed: 19299462
  10. Mesas-Burgos C et al. Gene expression analysis after prenatal tracheal ligation in fetal rat as a model of stimulated lung growth. J Pediatr Surg 44:720-8 (2009). PubMed: 19361631
  11. Duisters RF et al. miR-133 and miR-30 regulate connective tissue growth factor: implications for a role of microRNAs in myocardial matrix remodeling. Circ Res 104:170-8, 6p following 178 (2009). WB; Human. PubMed: 19096030
  12. Mitani A et al. Transcriptional coactivator with PDZ-binding motif is essential for normal alveolarization in mice. Am J Respir Crit Care Med 180:326-38 (2009). PubMed: 19498055
  13. Pala D et al. Focal Adhesion Kinase/Src Suppresses Early Chondrogenesis: CENTRAL ROLE OF CCN2. J Biol Chem 283:9239-9247 (2008). WB. PubMed: 18276598
  14. Kato T et al. AGEs-RAGE system mediates atrial structural remodeling in the diabetic rat. J Cardiovasc Electrophysiol 19:415-20 (2008). WB; Rat. PubMed: 18298515
  15. Hora C et al. Connective tissue growth factor, steatosis and fibrosis in patients with chronic hepatitis C. Liver Int 28:370-6 (2008). PubMed: 17976159
  16. Fernández P et al. Pharmacological blockade of A2A receptors prevents dermal fibrosis in a model of elevated tissue adenosine. Am J Pathol 172:1675-82 (2008). WB, IHC-P; Mouse. PubMed: 18467695
  17. Smith MM et al. Significant synovial pathology in a meniscectomy model of osteoarthritis: modification by intra-articular hyaluronan therapy. Rheumatology (Oxford) 47:1172-8 (2008). IHC-P; Sheep. PubMed: 18565987
  18. Kuiper EJ et al. Effect of VEGF-A on expression of profibrotic growth factor and extracellular matrix genes in the retina. Invest Ophthalmol Vis Sci 48:4267-76 (2007). PubMed: 17724216
  19. Manetti M et al. Severe fibrosis and increased expression of fibrogenic cytokines in the gastric wall of systemic sclerosis patients. Arthritis Rheum 56:3442-7 (2007). IHC-P; Human. PubMed: 17907149
  20. Mezzano S et al. Expression of gremlin, a bone morphogenetic protein antagonist, in glomerular crescents of pauci-immune glomerulonephritis. Nephrol Dial Transplant 22:1882-90 (2007). PubMed: 17403698
  21. Xie S et al. Mechanisms of induction of airway smooth muscle hyperplasia by transforming growth factor-beta. Am J Physiol Lung Cell Mol Physiol 293:L245-53 (2007). WB; Human. PubMed: 17468136
  22. Yevdokimova N & Podpryatov S The up-regulation of angiotensin II receptor type 1 and connective tissue growth factor are involved in high-glucose-induced fibronectin production by cultured human dermal fibroblasts. J Dermatol Sci 47:127-39 (2007). PubMed: 17399955
  23. Guha M et al. Specific down-regulation of connective tissue growth factor attenuates progression of nephropathy in mouse models of type 1 and type 2 diabetes. FASEB J 21:3355-68 (2007). WB, IHC-P; Mouse. PubMed: 17554073
  24. Koepke ML et al. Nephroprotective effect of the HMG-CoA-reductase inhibitor cerivastatin in a mouse model of progressive renal fibrosis in Alport syndrome. Nephrol Dial Transplant 22:1062-9 (2007). PubMed: 17287218
  25. Burgess JK et al. Connective tissue growth factor and vascular endothelial growth factor from airway smooth muscle interact with the extracellular matrix. Am J Physiol Lung Cell Mol Physiol 290:L153-61 (2006). IP; Human. PubMed: 16100286
  26. Portik-Dobos V et al. Endothelin antagonism prevents early EGFR transactivation but not increased matrix metalloproteinase activity in diabetes. Am J Physiol Regul Integr Comp Physiol 290:R435-41 (2006). PubMed: 16239374
  27. Gómez-Garre D et al. Losartan improves resistance artery lesions and prevents CTGF and TGF-beta production in mild hypertensive patients. Kidney Int 69:1237-44 (2006). PubMed: 16482098
  28. Dean RG et al. Connective tissue growth factor and cardiac fibrosis after myocardial infarction. J Histochem Cytochem 53:1245-56 (2005). PubMed: 15956033
  29. Zhao Z et al. Connective tissue growth factor (CTGF) expression in the brain is a downstream effector of insulin resistance- associated promotion of Alzheimer's disease beta-amyloid neuropathology. FASEB J 19:2081-2 (2005). PubMed: 16186174
  30. Xie S et al. Regulation of TGF-beta 1-induced connective tissue growth factor expression in airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol 288:L68-76 (2005). WB; Human. PubMed: 15377500
  31. Shin JY et al. HCV core protein promotes liver fibrogenesis via up-regulation of CTGF with TGF-beta1. Exp Mol Med 37:138-45 (2005). PubMed: 15886528
  32. Pi L et al. Role of connective tissue growth factor in oval cell response during liver regeneration after 2-AAF/PHx in rats. Gastroenterology 128:2077-88 (2005). PubMed: 15940639
  33. Ozaki S et al. Diffuse expression of heparan sulfate proteoglycan and connective tissue growth factor in fibrous septa with many mast cells relate to unresolving hepatic fibrosis of congenital hepatic fibrosis. Liver Int 25:817-28 (2005). PubMed: 15998433
  34. Gross O et al. Nephroprotection by antifibrotic and anti-inflammatory effects of the vasopeptidase inhibitor AVE7688. Kidney Int 68:456-63 (2005). PubMed: 16014022
  35. Danda RS et al. Kidney involvement in a nongenetic rat model of type 2 diabetes. Kidney Int 68:2562-71 (2005). PubMed: 16316331
  36. Bäcklund T et al. Sustained cardiomyocyte apoptosis and left ventricular remodelling after myocardial infarction in experimental diabetes. Diabetologia 47:325-30 (2004). PubMed: 14722653
  37. Gross O et al. Antifibrotic, nephroprotective potential of ACE inhibitor vs AT1 antagonist in a murine model of renal fibrosis. Nephrol Dial Transplant 19:1716-23 (2004). PubMed: 15128880
  38. Pörsti I et al. High calcium diet down-regulates kidney angiotensin-converting enzyme in experimental renal failure. Kidney Int 66:2155-66 (2004). PubMed: 15569305
  39. Hoek K et al. Expression profiling reveals novel pathways in the transformation of melanocytes to melanomas. Cancer Res 64:5270-82 (2004). PubMed: 15289333
  40. Ueberham U et al. Connective tissue growth factor in Alzheimer's disease. Neuroscience 116:1-6 (2003). PubMed: 12535930
  41. Finckenberg P et al. Angiotensin II induces connective tissue growth factor gene expression via calcineurin-dependent pathways. Am J Pathol 163:355-66 (2003). PubMed: 12819040
  42. Inkinen K et al. Connective tissue growth factor and its correlation to other growth factors in experimental granulation tissue. Connect Tissue Res 44:19-29 (2003). PubMed: 12945801
  43. Fu M et al. Peroxisome proliferator-activated receptor gamma inhibits transforming growth factor beta-induced connective tissue growth factor expression in human aortic smooth muscle cells by interfering with Smad3. J Biol Chem 276:45888-94 (2001). PubMed: 11590167

Publishing research using ab6992? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"