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CX3CR1 peptide (Human) (ab8125)

Abreviews (1)Q&A (1)

Overview

  • Product nameCX3CR1 peptide (Human)See all CX3CR1 proteins and peptides ...
  • Protein descriptionDQFPESVTENFEYDDLAEAC; 20 amino amino terminus of human CX3CR1

    • Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPBS with 0.1% BSA 0.02% sodium azide pH7.2
  • Concentration information loading...
  • Sequence notesDQFPESVTENFEYDDLAEAC
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab8125 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    Blocking
  • Application notesThe peptide is used for blocking the activity of anti-CX3CR1 ab8021. Incubating the peptide with equal volume of antibody for 30 min at 37°C usually completely blocksthe antibody activity in Western blotting.

    • Protein info

    • Alternative names
        Beta chemokine receptor-like 1C X3 C CKR 1C-X3-C CKR-1
        CCRL1Chemokine C X3 C motif receptor 1CMK BRL 1CMK-BRL-1CMK-BRL1CMKBLR1CMKDR1CX3C chemokine receptor 1CX3C CKR1CX3C1_HUMANCX3CR1Fractalkine ReceptorG-protein coupled receptor 13GPR13GPRV28V28
      see all
  • FunctionReceptor for the CX3C chemokine fractalkine and mediates both its adhesive and migratory functions. Acts as coreceptor with CD4 for HIV-1 virus envelope protein (in vitro). Isoform 2 and isoform 3 seem to be more potent HIV-1 coreceptors than isoform 1.
  • Tissue specificityExpressed in lymphoid and neural tissues.
  • Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
  • Cellular localizationCell membrane.

    • Target information above from: UniProt accession P49238 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    References for CX3CR1 peptide (Human) (ab8125)

    ab8125 has not yet been referenced specifically in any publications.

    Publishing research using ab8125 ? Please let us know so that we can cite the reference in this datasheet

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    Submit an Abreview for ab8125 Submit a Question for ab8125

    Displaying 1 - 2 of 2 results for Abreviews and Q&A

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    Dear technical team, Our customer purchased ab8021 and stained xxxxx and observed with confocal. She got good results but her professor doesn't believe this data. There's no reference CX3CR1 detected in this tissue untilnow by his knowledge. So, the cust...

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    Thank you for contacting us. I am happy to hear that your customer has exciting results. I suggest to include additional control to verify these results: The blocking peptide can be used to show that the antibody binds specifically. If the antibody is inc...

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    Other (Immunohistochemistry peptide block) Abreview for CX3CR1 peptide (Human)

     Excellent
    Abreviews
    Application Other

    Review text: Used as a control for blocking the activity of anti-CX3CR1 (ab8021) in immunohistochemistry frozen sections. Peptide was incubated with an equal volume of antibody at 37*C for 30 mins before applying to sections diluted 1:400 in PBS.
    Sample: Mouse Tissue sections

    Primary antibody (in addition to 'CX3CR1 peptide (Human)')
    Primary antibody: Abcam primary antibody: Anti-CX3CR1 antibody (ab8021)
    Dilution: 1/400

    Secondary antibody
    Name: Non-Abcam antibody was used: Alexa Fluor® 568 goat anti-rabbit IgG (H+L) *2 mg/
    Host species: Goat
    Clonality: Polyclonal
    Conjugation: Alexa Fluor® 568
    Dilution: 1/800
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    Verified customer

    Submitted Nov 30 2010

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"