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Anti-CXCR4 antibody (ab2074)

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Publishing research using ab2074? Please let us know so that we can cite the reference in this datasheet

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ab2074 has been referenced in 34 publications.

  1. Wynn RF et al. A small proportion of mesenchymal stem cells strongly express functionally active CXCR4 receptor capable of promoting migration to bone marrow. Blood : (2004). PubMed: 15251986
  2. Castellone MD et al. Functional expression of the CXCR4 chemokine receptor is induced by RET/PTC oncogenes and is a common event in human papillary thyroid carcinomas. Oncogene 23:5958-67 (2004). PubMed: 15184868
  3. Rupertus K et al. Bone Marrow Suppression by c-Kit Blockade Enhances Tumor Growth of Colorectal Metastases through the Action of Stromal Cell-Derived Factor-1. J Oncol 2012:196957 (2012). WB; Mouse. PubMed: 21977032
  4. Boudot A et al. Differential Estrogen-Regulation of CXCL12 Chemokine Receptors, CXCR4 and CXCR7, Contributes to the Growth Effect of Estrogens in Breast Cancer Cells. PLoS One 6:e20898 (2011). WB; Human. PubMed: 21695171
  5. Saini V et al. The CXC Chemokine Receptor 4 Ligands Ubiquitin and Stromal Cell-derived Factor-1{alpha} Function through Distinct Receptor Interactions. J Biol Chem 286:33466-77 (2011). PubMed: 21757744
  6. Nasser MW et al. Crosstalk between Chemokine Receptor CXCR4 and Cannabinoid Receptor CB(2) in Modulating Breast Cancer Growth and Invasion. PLoS One 6:e23901 (2011). WB, IHC-P; Human. PubMed: 21915267
  7. Neusser MA et al. Human nephrosclerosis triggers a hypoxia-related glomerulopathy. Am J Pathol 176:594-607 (2010). IHC; Human. PubMed: 20019191
  8. Gilli F et al. Learning from nature: pregnancy changes the expression of inflammation-related genes in patients with multiple sclerosis. PLoS One 5:e8962 (2010). WB; Human. PubMed: 20126412
  9. Graumann U et al. CD133 expressing pericytes and relationship to SDF-1 and CXCR4 in spinal cord injury. Curr Neurovasc Res 7:144-54 (2010). IHC-Fr; Rat. PubMed: 20374199
  10. Southgate TD et al. CXCR4 mediated chemotaxis is regulated by 5T4 oncofetal glycoprotein in mouse embryonic cells. PLoS One 5:e9982 (2010). WB, ICC/IF; Mouse. PubMed: 20376365
  11. Saini V et al. CXC chemokine receptor 4 is a cell surface receptor for extracellular ubiquitin. J Biol Chem 285:15566-76 (2010). WB; Human. PubMed: 20228059
  12. Rehimi R et al. A novel role of CXCR4 and SDF-1 during migration of cloacal muscle precursors. Dev Dyn 239:1622-31 (2010). IHC-P; Mouse. PubMed: 20503359
  13. Griffin CA et al. Chemokine expression and control of muscle cell migration during myogenesis. J Cell Sci 123:3052-60 (2010). WB; Mouse. PubMed: 20736301
  14. Campbell GR et al. HIV-1 clade B Tat, but not clade C Tat, increases X4 HIV-1 entry into resting but not activated CD4+ T cells. J Biol Chem 285:1681-91 (2010). WB; Human. PubMed: 19917610
  15. Rajagopal S et al. Beta-arrestin- but not G protein-mediated signaling by the "decoy" receptor CXCR7. Proc Natl Acad Sci U S A 107:628-32 (2010). WB; Human. PubMed: 20018651
  16. Zhu J et al. Persistence of HIV-1 receptor-positive cells after HSV-2 reactivation is a potential mechanism for increased HIV-1 acquisition. Nat Med 15:886-92 (2009). IHC-Fr; Human. PubMed: 19648930
  17. Hong JS et al. CXCR-4 knockdown by small interfering RNA inhibits cell proliferation and invasion of oral squamous cell carcinoma cells. J Oral Pathol Med 38:214-9 (2009). WB. PubMed: 18624931
  18. Ierano C et al. A point mutation (G574A) in the chemokine receptor CXCR4 detected in human cancer cells enhances migration. Cell Cycle 8:1228-37 (2009). WB; Human. PubMed: 19305148
  19. Grundler R et al. Dissection of PIM serine/threonine kinases in FLT3-ITD-induced leukemogenesis reveals PIM1 as regulator of CXCL12-CXCR4-mediated homing and migration. J Exp Med 206:1957-70 (2009). ICC/IF; Human. PubMed: 19687226
  20. Kwong J et al. An antagonist of the chemokine receptor CXCR4 induces mitotic catastrophe in ovarian cancer cells. Mol Cancer Ther 8:1893-905 (2009). PubMed: 19567818
  21. Yang D et al. The A2b adenosine receptor protects against vascular injury. Proc Natl Acad Sci U S A 105:792-6 (2008). WB; Mouse. PubMed: 18184815
  22. Jin L et al. CXCR4 up-regulation by imatinib induces chronic myelogenous leukemia (CML) cell migration to bone marrow stroma and promotes survival of quiescent CML cells. Mol Cancer Ther 7:48-58 (2008). IHC-P; Human. PubMed: 18202009
  23. Ghosh MC et al. Dexamethasone augments CXCR4-mediated signaling in resting human T cells via the activation of the Src kinase Lck. Blood : (2008). PubMed: 18840710
  24. Begley LA et al. CXCL12 activates a robust transcriptional response in human prostate epithelial cells. J Biol Chem 282:26767-74 (2007). WB; Human. PubMed: 17631494
  25. Schade B et al. Distinct ErbB-2 coupled signaling pathways promote mammary tumors with unique pathologic and transcriptional profiles. Cancer Res 67:7579-88 (2007). PubMed: 17699761
  26. Moutsopoulos NM et al. Tonsil epithelial factors may influence oropharyngeal human immunodeficiency virus transmission. Am J Pathol 171:571-9 (2007). PubMed: 17620369
  27. Zhang M et al. SDF-1 expression by mesenchymal stem cells results in trophic support of cardiac myocytes after myocardial infarction. FASEB J 21:3197-207 (2007). IHC; Rat. PubMed: 17496162
  28. Ding M et al. Loss of the tumor suppressor Vhlh leads to upregulation of Cxcr4 and rapidly progressive glomerulonephritis in mice. Nat Med 12:1081-7 (2006). PubMed: 16906157
  29. Begley L et al. CXCL12 overexpression and secretion by aging fibroblasts enhance human prostate epithelial proliferation in vitro. Aging Cell 4:291-8 (2005). PubMed: 16300481
  30. Busso N et al. Circulating CD26 is negatively associated with inflammation in human and experimental arthritis. Am J Pathol 166:433-42 (2005). IHC-P; Mouse. PubMed: 15681827
  31. Smith MC et al. CXCR4 regulates growth of both primary and metastatic breast cancer. Cancer Res 64:8604-12 (2004). PubMed: 15574767
  32. Spano JP et al. Chemokine receptor CXCR4 and early-stage non-small cell lung cancer: pattern of expression and correlation with outcome. Ann Oncol 15:613-7 (2004). PubMed: 15033669
  33. Li YM et al. Upregulation of CXCR4 is essential for HER2-mediated tumor metastasis. Cancer Cell 6:459-69 (2004). PubMed: 15542430
  34. Taichman RS et al. Use of the stromal cell-derived factor-1/CXCR4 pathway in prostate cancer metastasis to bone. Cancer Res 62:1832-7 (2002). PubMed: 11912162

Publishing research using ab2074? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"