Anti-CYB5R2 antibody (ab126137)

Overview

• Product nameAnti-CYB5R2 antibodySee all CYB5R2 primary antibodies ...
• Description
  Rabbit polyclonal to CYB5R2
• Tested applicationsWB more details
• Species reactivity
  Reacts with: Human
  Predicted to work with: Mouse, Rat
• Immunogen

  Recombinant fragment, corresponding to a region within amino acids 1-182 of Human CYB5R2 (Q6BCY4).

• Positive controlPC3, U-87 MG and SK N SH whole cell lysates.
• General notesStore as concentrated solution

Properties

• FormLiquid
• Storage instructionsStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Storage bufferpH: 7.00
  Preservative: 0.01% Thimerosal (merthiolate)
  Constituents: 78% PBS, 20% Glycerol, 1% BSA
• Concentration information loading...
• PurityImmunogen affinity purified
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Metabolism
  • Types of disease
  • Cancer

  • Metabolism
  • Pathways and Processes
  • Metabolic signaling pathways
  • Lipid and lipoprotein metabolism
  • Lipases

  • Metabolism
  • Pathways and Processes
  • Mitochondrial Metabolism
  • Mitochondrial markers

  • Metabolism
  • Pathways and Processes
  • Mitochondrial Metabolism
  • Cytochromes

  • Metabolism
  • Pathways and Processes
  • Redox metabolism
  • Oxidative stress

  • Signal Transduction
  • Metabolism
  • Lipid metabolism

  • Signal Transduction
  • Metabolism
  • Mitochondrial

  • Cardiovascular
  • Lipids / Lipoproteins
  • Lipid Metabolism
  • Cytochromes

  • Cell Biology
  • Other Antibodies
  • Oxidative Stress

Applications

Target

• FunctionNADH-cytochrome b5 reductases are involved in desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction (By similarity). Responsible for NADH-dependent lucigenin chemiluminescence in spermatozoa by reducing both lucigenin and 2-[4-iodophenyl]-3-[4-nitrophenyl]-5-[2,4-disulfophenyl]-2H tetrazolium monosodium salt (WST-1).
• Tissue specificityRestricted expression.
• Sequence similaritiesBelongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
  Contains 1 FAD-binding FR-type domain.

Target information above from: UniProt accession Q6BCY4 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 51700 Human
  • Entrez Gene: 51700 Human
  • Entrez Gene: 320635 Mouse
  • Entrez Gene: 365345 Rat
  • Omim: 608342 Human
  • SwissProt: Q6BCY4 Human
  • SwissProt: Q6BCY4 Human
  • SwissProt: Q3KNK3 Mouse

  • SwissProt: Q6AY12 Rat
  • Unigene: 414362 Human
  • Unigene: 132828 Mouse
  • Unigene: 16198 Rat

  see all

• Alternative names
  b5R.2 antibodyCyb5r2 antibodyCytochrome b5 reductase 2 antibody

  Cytochrome b5 reductase b5R.2 antibodyNADH cytochrome b5 reductase 2 antibodyNADH-cytochrome b5 reductase 2 antibodyNB5R2_HUMAN antibody

  see all

Anti-CYB5R2 antibody images

• 

  Western blot - Anti-CYB5R2 antibody (ab126137)
  All lanes : Anti-CYB5R2 antibody (ab126137) at 1/1000 dilution
  
  Lane 1 : PC3 whole cell lysate
  Lane 2 : U-87 MG whole cell lysate
  Lane 3 : SK N SH whole cell lysate
  
  Lysates/proteins at 30 µg per lane.
  
  
  Predicted band size : 31 kDa