Overview
- Product nameAnti-CYFIP2 antibodySee all CYFIP2 primary antibodies ...
- DescriptionRabbit polyclonal to CYFIP2
- Conjugation notesab95969 was purified by antigen affinity chromatography.
- Tested applicationsWB, IHC-P more details
- Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat, Zebrafish - Immunogen
Recombinant fragment, corresponding to a region within amino acids 346-610 of Human CYFIP2 (UniProt ID: Q96F07 isoform 2; NP_055191).
- Positive controlWB: MOLT4 whole cell lysate; Raji cell lysate IHC-P: NCIN87 xenograft
Properties
- FormLiquid
- Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
- Storage bufferPreservative: 0.01% Thimerosal (merthiolate)
Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0 -
Concentration information loading... - PurityImmunogen affinity purified
- Clonality Polyclonal
- IsotypeIgG
- Research Areas
Applications
Our Abpromise guarantee covers the use of ab95969 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Notes |
|---|---|
| WB | WB: 1/500 - 1/3000. Predicted molecular weight: 146 kDa. |
| IHC-P | IHC-P: 1/100 - 1/500. |
Target
- RelevanceCYFIP2 is involved in T cell adhesion and p53 dependent induction of apoptosis. It does not bind RNA but is up regulated significantly in CD4+ T lymphocytes from patients with multiple sclerosis. There are 2 isoforms produced by alternative splicing.
- Cellular localizationCytoplasm perinuclear region. Cell junction, synapse, synaptosome. Treatment with leptomycin-B triggers translocation to the nucleus.
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Database links
- Entrez Gene: 26999 Human
- Entrez Gene: 26999 Human
- Entrez Gene: 76884 Mouse
- Entrez Gene: 303073 Rat
- Entrez Gene: 100002872 Zebrafish
- Omim: 606323 Human
- SwissProt: Q96F07 Human
- SwissProt: Q96F07 Human
- SwissProt: Q5SQX6 Mouse
- Unigene: 910449 Human
- Unigene: 293961 Mouse
see all
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Alternative names
- CYFP2 antibodycytoplasmic FMR1 interacting protein 2 antibodyKIAA1168 antibody
- p53 inducible protein antibodyp53-inducible protein 121 antibodyPIR121 antibody
see all
Anti-CYFIP2 antibody images
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Western blot - CYFIP2 antibody (ab95969)Anti-CYFIP2 antibody (ab95969) at 1/1000 dilution + MOLT4 whole cell lysate at 30 µg
Predicted band size : 146 kDa -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CYFIP2 antibody (ab95969)ab95969, at a 1/100 dilution, staining CYFIP2 in paraffin embedded NCIN87 xenograft by Immunohistochemistry.
References for Anti-CYFIP2 antibody (ab95969)
This product has been referenced in:
- Mongroo PS et al. IMP-1 displays cross-talk with K-Ras and modulates colon cancer cell survival through the novel proapoptotic protein CYFIP2. Cancer Res 71:2172-82 (2011). WB ; Human . Read more (PubMed: 21252116) »
