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Western blot - CaMKI antibody - Carboxyterminal end (ab38002)
Western blot - CaMKI antibody - Carboxyterminal end (ab38002)
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CaMKI antibody - Carboxyterminal end (ab38002)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CaMKI antibody - Carboxyterminal end (ab38002)
(enlarge)


Product Name 

CaMKI antibody - Carboxyterminal end

 

See all CaMKI antibodies (9)...

Product type 

Primary antibodies

Description 

Rabbit polyclonal to CaMKI - Carboxyterminal end

Immunogen 

Synthetic peptide corresponding to the C terminal region of Human CaMKI conjugated to KLH

Reacts with 
(species key)

Hu

Tested applications 
(see key)

ELISA, IHC-P, WB


Abreviews 

Customer reviews
(see key)


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Application notes 
(see key)

Recommended dilutions
ELISA: 1/1000.
IHC-P: 1/50 - 1/100.
WB: 1/100 - 1/500. Detects a band of approximately 40 kDa (predicted molecular weight: 40 kDa).


Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Positive control 
(see definition)

NCIH460 cell lysate.

Cellular localization 

Cytoplasmic and Nuclear

Research areas 

Cardiovascular >> Heart >> Hypertrophy >> Other
Signal Transduction >> Signaling Pathway >> Calcium Signaling >> Calmodulin Pathway
Neuroscience >> Neurotransmission >> Calcium Signaling >> Calmodulin / CaMK

Relevance 

Calcium / calmodulin-dependent kinases (CaMKs) are a subfamily of the serine/threonine protein kinase family that includes CaMKI, CaMKII, and CaMKIV. There have been identified multiple substrates for CaMKI, including synapsin 1, synapsin 2, CREB, and CFTR, and its activation is dependent upon phosphorylation of Thr 177 by CaMK kinase (CaMKK). Studies suggest that CaMKI plays an important role in retinal function and its expression is regulated by light stimulation.

 

CaMKI antibody - Carboxyterminal end (ab38002)

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

8536    (Human)

Omim

    

604998    (Human)

SwissProt

    

Q14012    (Human)

Unigene

    

434875    (Human)

Raised in 

Rabbit

Clonality 

Polyclonal

Isotype 

IgG

Purity 

Protein G purified

Storage buffer 

Preservative: 0.09% Sodium Azide
Constituents: PBS

Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS

Form 

Liquid

Concentration 

0.250 mg/ml

Storage instructions 

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

 

At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this CaMKI antibody - Carboxyterminal end is on this datasheet. But please do contact us if you would like any reassurance!


See below for CaMKI antibody - Carboxyterminal end images, references, products related to ab38002 and other tools.

 

CaMKI antibody - Carboxyterminal end images:

Product image  Western blot - CaMKI antibody - Carboxyterminal end (ab38002)

Western blot - CaMKI antibody - Carboxyterminal end (ab38002)

CaMKI antibody - Carboxyterminal end (ab38002) at 1/100 dilution + NCIH460 cell lysate.
developed using the ECL technique

Predicted band size : 40 kDa
Observed band size : 40 kDa

 

Product image  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CaMKI antibody - Carboxyterminal end (ab38002)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CaMKI antibody - Carboxyterminal end (ab38002)

Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with 1/50 ab38002.

 
 

Search PubMed (MEDLINE) for references to CaMKI

 

CaMKI antibody - Carboxyterminal end - more information

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CaMKI antibody - Carboxyterminal end - related products:

Products for Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

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