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Products:Neuroscience >> Neurotransmission >> Calcium Signaling >> Calmodulin / CaMK
Overview
Product name
Anti-CaMKI antibody - Carboxyterminal end
See all CaMKI products (9) ...
Description
Rabbit polyclonal to CaMKI - Carboxyterminal end
Tested applications
ELISA, WB, IHC-Pmore details
Cross reactivity
Reacts with
Human
Immunogen
Synthetic peptide corresponding to the C terminal region of Human CaMKI conjugated to KLH
Positive control
NCIH460 cell lysate.
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 0.09% Sodium Azide
Constituents: PBS
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Cardiovascular >> Heart >> Hypertrophy >> Other
Signal Transduction >> Signaling Pathway >> Calcium Signaling >> Calmodulin Pathway
Neuroscience >> Neurotransmission >> Calcium Signaling >> Calmodulin / CaMK
Applications
Show applications key
Our Abpromise guarantee covers the use of ab38002 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
ELISA
ELISA: 1/1000ELISA: 1/1000
WB: 1/100 - 1/500.Detects a band of approximately 40 kDa (predicted molecular weight: 40 kDa).
IHC-P: 1/50 - 1/100.
Target
Relevance
Calcium / calmodulin-dependent kinases (CaMKs) are a subfamily of the serine/threonine protein kinase family that includes CaMKI, CaMKII, and CaMKIV. There have been identified multiple substrates for CaMKI, including synapsin 1, synapsin 2, CREB, and CFTR, and its activation is dependent upon phosphorylation of Thr 177 by CaMK kinase (CaMKK). Studies suggest that CaMKI plays an important role in retinal function and its expression is regulated by light stimulation.
Cellular localization
Cytoplasmic and Nuclear
Alternative names
- Calcium / calmodulin dependent protein kinase 1 antibody
- Calcium / calmodulin dependent protein kinase I antibody
- Calcium / calmodulin dependent protein kinase type 1 antibody
see all
Database links
- Entrez Gene: 8536 Human
- Omim: 604998 Human
- SwissProt: Q14012 Human
- Unigene: 434875 Human
Anti-CaMKI antibody - Carboxyterminal end images:
Western blot - CaMKI antibody - Carboxyterminal end (ab38002)
Anti-CaMKI antibody - Carboxyterminal end (ab38002) at 1/100 dilution + NCIH460 cell lysate.
developed using the ECL technique
Predicted band size : 40 kDa
Observed band size : 40 kDa
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CaMKI antibody - Carboxyterminal end (ab38002)
Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with 1/50 ab38002.
References for Anti-CaMKI antibody - Carboxyterminal end (ab38002)
ab38002 has not yet been referenced specifically in any publications.
Publishing research using ab38002? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"