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Products:Neuroscience >> Neurotransmission >> Calcium Signaling >> Calmodulin / CaMK
Overview
Product name
Anti-CaMKI antibody
See all CaMKI products (9) ...
Description
Rabbit polyclonal to CaMKI
Specificity
Detects CaMKI from rat brain extract.
Tested applications
Cross reactivity
Reacts with
Rat
Predicted to work with
Human
Immunogen
Synthetic peptide: AVEGPRWKQAEDIRDIYD, corresponding to amino acids 1-18 of Human CaMKI.
AVEGPRWKQA EDIRDIYD
Positive control
AtT20 cell extract.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
PBS, 1 mg/ml BSA and 0.05% sodium azide
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Cardiovascular >> Heart >> Hypertrophy >> Other
Signal Transduction >> Signaling Pathway >> Calcium Signaling >> Calmodulin Pathway
Neuroscience >> Neurotransmission >> Calcium Signaling >> Calmodulin / CaMK
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Western blot - CaMKI antibody (ab3551)
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Applications
Show applications key
Our Abpromise guarantee covers the use of ab3551 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 1 Image
WB
Application notes
WB: Use at a concentration of 2 µg/ml. Predicted molecular weight: 41 kDa.
By Western blot, this antibody detects an ~43 kDa protein representing CaMKI from rat brain extract.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Relevance
Calcium / calmodulin-dependent kinases (CaMKs) are a subfamily of the serine/threonine protein kinase family that includes CaMKI, CaMKII, and CaMKIV. There have been identified multiple substrates for CaMKI, including synapsin 1, synapsin 2, CREB, and CFTR, and its activation is dependent upon phosphorylation of Thr 177 by CaMK kinase (CaMKK). Studies suggest that CaMKI plays an important role in retinal function and its expression is regulated by light stimulation.
Cellular localization
Cytoplasmic and Nuclear
Alternative names
- Calcium / calmodulin dependent protein kinase 1 antibody
- Calcium / calmodulin dependent protein kinase I antibody
- Calcium / calmodulin dependent protein kinase type 1 antibody
see all
Database links
- Entrez Gene: 8536 Human
- Entrez Gene: 171503 Rat
- Omim: 604998 Human
- SwissProt: Q14012 Human
- SwissProt: Q63450 Rat
- Unigene: 434875 Human
- Unigene: 11018 Rat
Anti-CaMKI antibody images:
Western blot - CaMKI antibody (ab3551)
Anti-CaMKI antibody (ab3551) at 2 µg/ml + Cell lysate prepared from AtT20 cells
Predicted band size : 41 kDa
References for Anti-CaMKI antibody (ab3551)
ab3551 has not yet been referenced specifically in any publications.
Publishing research using ab3551? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"