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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CaMKI antibody (ab62683)
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Product Name
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CaMKI antibody
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See all CaMKI antibodies (9)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to CaMKI
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Immunogen
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Synthetic non-phosphopeptide derived from human CaMKI around the phosphorylation site of threonine 177 (L-S-TP-A-C).
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Reacts with
(species key)
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Hu, Ms, Rat
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Tested applications
(see key)
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ELISA, IHC-P
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Abreviews
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Application notes
(see key)
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Recommended dilutions
ELISA: 1/5000.
IHC-P: 1/50 - 1/100.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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Human breast carcinoma tissue.
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Cellular localization
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Cytoplasmic and Nuclear
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Research areas
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Cardiovascular >> Heart >> Hypertrophy >> Other
Signal Transduction >> Signaling Pathway >> Calcium Signaling >> Calmodulin Pathway
Neuroscience >> Neurotransmission >> Calcium Signaling >> Calmodulin / CaMK
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Relevance
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Calcium / calmodulin-dependent kinases (CaMKs) are a subfamily of the serine/threonine protein kinase family that includes CaMKI, CaMKII, and CaMKIV. There have been identified multiple substrates for CaMKI, including synapsin 1, synapsin 2, CREB, and CFTR, and its activation is dependent upon phosphorylation of Thr 177 by CaMK kinase (CaMKK). Studies suggest that CaMKI plays an important role in retinal function and its expression is regulated by light stimulation.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Immunogen affinity purified
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Storage buffer
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Preservative: 0.02% Sodium Azide
Constituents: 50% Glycerol, PBS, 150mM Sodium chloride, pH 7.4 Material safety datasheets (MSDS) for this product:
Glycerol MSDS
Sodium Azide MSDS
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Store at -20°C. Stable for 12 months at -20°C
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this CaMKI antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for CaMKI antibody images, references, products related to ab62683 and other tools.
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CaMKI antibody images:
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 Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CaMKI antibody (ab62683)
ab62683 at 1/50 - 1/100 dilution staining CaMKI in human breast carcinoma by Immunohistochemistry, Paraffin-embedded tissue, in the absence or presence of the immunising peptide.
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Search PubMed (MEDLINE) for references to CaMKI
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CaMKI antibody - more information
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Customer reviews (feedback) regarding CaMKI antibody |
Customer FAQs regarding CaMKI antibody |
Protocols for CaMKI antibody |
Price and availability of products related to CaMKI antibody |
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CaMKI antibody - related products:
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CaMKI antibody - other tools:
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Contact Abcam with a Technical Enquiry about CaMKI antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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