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Anti-CaMKI antibody (ab62683)

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Overview

Product name

Anti-CaMKI antibody
See all CaMKI products (9) ...

Description

Rabbit polyclonal to CaMKI

Tested applications

ELISA, IHC-Pmore details

Cross reactivity

Reacts with

Mouse, Rat, Human

Immunogen

Synthetic non-phosphopeptide derived from human CaMKI around the phosphorylation site of threonine 177 (L-S-TP-A-C).

Positive control

Human breast carcinoma tissue.

Properties

Form

Liquid

Storage instructions

Store at -20°C. Stable for 12 months at -20°C

Storage buffer

Preservative: 0.02% Sodium Azide
Constituents: 50% Glycerol, PBS, 150mM Sodium chloride, pH 7.4

Concentration

Concentration information loading...

Purity

Immunogen affinity purified

Clonality

Polyclonal

Isotype

IgG

Research areas

Cardiovascular >> Heart >> Hypertrophy >> Other
Signal Transduction >> Signaling Pathway >> Calcium Signaling >> Calmodulin Pathway
Neuroscience >> Neurotransmission >> Calcium Signaling >> Calmodulin / CaMK

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CaMKI antibody (ab62683)Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CaMKI antibody (ab62683) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab62683 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • ELISA

     ELISA: 1/5000

    ELISA: 1/5000

  • 1 Image

    IHC-P

     IHC-P: 1/50 - 1/100.

    IHC-P: 1/50 - 1/100.

Target

Relevance

Calcium / calmodulin-dependent kinases (CaMKs) are a subfamily of the serine/threonine protein kinase family that includes CaMKI, CaMKII, and CaMKIV. There have been identified multiple substrates for CaMKI, including synapsin 1, synapsin 2, CREB, and CFTR, and its activation is dependent upon phosphorylation of Thr 177 by CaMK kinase (CaMKK). Studies suggest that CaMKI plays an important role in retinal function and its expression is regulated by light stimulation.

Cellular localization

Cytoplasmic and Nuclear

Alternative names

  • Calcium / calmodulin dependent protein kinase 1 antibody
  • Calcium / calmodulin dependent protein kinase I antibody
  • Calcium / calmodulin dependent protein kinase type 1 antibody
  • Calcium/calmodulin dependent protein kinase 1 antibody
  • Calcium/calmodulin dependent protein kinase I antibody
  • Calcium/calmodulin dependent protein kinase type 1 antibody
  • CaM K1 antibody
  • CaM KI antibody
  • CaM kinase 1 alpha antibody
  • CAM kinase 1 antibody
  • CaM kinase I alpha antibody
  • CAM kinase I antibody
  • CaMK 1 antibody
  • CAMK I antibody
  • CaMK1 alpha antibody
  • CaMK1 antibody
  • CAMK1 PEN antibody
  • CaMKI alpha antibody
  • MGC120317 antibody
  • MGC120318 antibody
see all

Database links

see all

Anti-CaMKI antibody images:

  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CaMKI antibody (ab62683)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CaMKI antibody (ab62683)

ab62683 at 1/50 - 1/100 dilution staining CaMKI in human breast carcinoma by Immunohistochemistry, Paraffin-embedded tissue, in the absence or presence of the immunising peptide.

References for Anti-CaMKI antibody (ab62683)

ab62683 has not yet been referenced specifically in any publications.

Publishing research using ab62683? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"