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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CaMKI antibody (ab62683)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CaMKI antibody (ab62683)
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Product Name 

CaMKI antibody

 

See all CaMKI antibodies (9)...

Product type 

Primary antibodies

Description 

Rabbit polyclonal to CaMKI

Immunogen 

Synthetic non-phosphopeptide derived from human CaMKI around the phosphorylation site of threonine 177 (L-S-TP-A-C).

Reacts with 
(species key)

Hu, Ms, Rat

Tested applications 
(see key)

ELISA, IHC-P


Abreviews 

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(see key)


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Application notes 
(see key)

Recommended dilutions
ELISA: 1/5000.
IHC-P: 1/50 - 1/100.

Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Positive control 
(see definition)

Human breast carcinoma tissue.

Cellular localization 

Cytoplasmic and Nuclear

Research areas 

Cardiovascular >> Heart >> Hypertrophy >> Other
Signal Transduction >> Signaling Pathway >> Calcium Signaling >> Calmodulin Pathway
Neuroscience >> Neurotransmission >> Calcium Signaling >> Calmodulin / CaMK

Relevance 

Calcium / calmodulin-dependent kinases (CaMKs) are a subfamily of the serine/threonine protein kinase family that includes CaMKI, CaMKII, and CaMKIV. There have been identified multiple substrates for CaMKI, including synapsin 1, synapsin 2, CREB, and CFTR, and its activation is dependent upon phosphorylation of Thr 177 by CaMK kinase (CaMKK). Studies suggest that CaMKI plays an important role in retinal function and its expression is regulated by light stimulation.

 

Alternative names CaMKI antibody (ab62683)

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

8536    (Human)
52163    (Mouse)
171503    (Rat)

Omim

    

604998    (Human)

SwissProt

    

Q14012    (Human)
Q91YS8    (Mouse)
Q63450    (Rat)

Unigene

    

434875    (Human)
11018    (Rat)

Raised in 

Rabbit

Clonality 

Polyclonal

Isotype 

IgG

Purity 

Immunogen affinity purified

Storage buffer 

Preservative: 0.02% Sodium Azide
Constituents: 50% Glycerol, PBS, 150mM Sodium chloride, pH 7.4

Material safety datasheets (MSDS) for this product:
Glycerol MSDS
Sodium Azide MSDS

Form 

Liquid

Concentration 

1.000 mg/ml

Storage instructions 

Store at -20°C. Stable for 12 months at -20°C

 

At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this CaMKI antibody is on this datasheet. But please do contact us if you would like any reassurance!


See below for CaMKI antibody images, references, products related to ab62683 and other tools.

 

CaMKI antibody images:

Product image  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CaMKI antibody (ab62683)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CaMKI antibody (ab62683)

ab62683 at 1/50 - 1/100 dilution staining CaMKI in human breast carcinoma by Immunohistochemistry, Paraffin-embedded tissue, in the absence or presence of the immunising peptide.

 
 

Search PubMed (MEDLINE) for references to CaMKI

 

CaMKI antibody - more information

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CaMKI antibody - related products:

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