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Overview

  • Product nameCaMKI gamma protein (Active)See all CaMKI gamma proteins and peptides ...
  • Protein descriptionRecombinant fusion protein, corresponding to N terminal amino acids 1-330 of Human CaMKI gamma, expressed by baculovirus in Sf9 insect cells with an N-terminal tag.
  • Expression hostBaculovirus infected sf9 cells

    • Properties

  • Purification notesPurity determined to be > 90% by densitometry.
  • Biological activitySpecific activity was determined to be 788 nmol/min/mg.
  • FormLiquid
  • Storage instructionsShipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.This product is an active protein and may elicit a biological response in vivo, handle with caution.
  • Storage bufferPreservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5
  • Concentration information loading...
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab51400 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    SDS-PAGE
    Functional Studies
  • Application notesKinase activity assay. Use at an assay dependent dilution.
    SDS-PAGE: Use at an assay dependent dilution.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.

    • Protein info

    • Alternative names
        Calcium/calmodulin dependent protein kinase type 1GCalcium/calmodulin-dependent protein kinase type 1GCaM kinase I gamma
        CaM kinase IGCaM-KI gammaCaMK like CREB kinase IIICaMK-like CREB kinase IIICamk1gCaMKI gammaCaMKIGCLICK IIIKCC1G_HUMAN
      see all
  • FunctionCalcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. In vitro phosphorylates transcription factor CREB1.
  • Tissue specificityMainly expressed in brain with small amounts in skeletal muscles, kidney, spleen and liver. Strongly expressed in forebrain neocortex, striatum and limbic system.
  • Sequence similaritiesBelongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
    Contains 1 protein kinase domain.
  • DomainThe autoinhibitory domain overlaps with the calmodulin binding region and interacts in the inactive folded state with the catalytic domain as a pseudosubstrate.
  • Post-translational
    modifications    May be prenylated on Cys-473.
  • Cellular localizationCytoplasm. Golgi apparatus membrane. Cell membrane.

    • Target information above from: UniProt accession Q96NX5 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    CaMKI gamma protein (Active) images

    • Functional Studies - CaMKI gamma protein (ab51400)
      Functional Studies - CaMKI gamma protein (ab51400)
      Kinase activity assay. Specific activity 788 nmol/min/mg.
    • SDS-PAGE - CaMKI gamma protein (ab51400)
      SDS-PAGE - CaMKI gamma protein (ab51400)
      Recombinant human CaMKI gamma (with proprietary tag)
      molecular weight 69 kDa.

    References for CaMKI gamma protein (Active) (ab51400)

    ab51400 has not yet been referenced specifically in any publications.

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