You have changed your country from  to  . Please be aware that this will change the currency in the purchasing process.

Related products

Reassurance, Refunds & Replacements

If your product does not perform as described on this datasheet, we will refund or replace your product...

Read our guarantee »
 

Anti-CaMKII alpha antibody (ab50202)

CodeSizePriceAbpointsAvailability
    
 
  • -
  •   
  •   
  •   
  •  
  •   
  •   
Updating...

Overview

Product name

Anti-CaMKII alpha antibody
See all CaMKII alpha products (11) ...

Description

Rabbit polyclonal to CaMKII alpha

Specificity

ab50202 does not cross-react with CaMKIIß, g and d isoforms (60 kDa).

Tested applications

WB, IPmore details

Cross reactivity

Reacts with

Mouse, Rat, Chicken, Human

Predicted to work with

Cow, Zebrafish

Immunogen

Synthetic peptide: KWQIVHFHRSGAPSVLPH conjugated to KLH, corresponding to C terminal amino acids 461-478 of Rat CaMKII alpha

KWQIVHFHRS GAPSVLPH

Positive control

Synaptosomal fraction of rat brain

Properties

Form

Liquid

Storage instructions

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: 15mM Sodium Azide
Constituents: 0.01M PBS, pH 7.4

Concentration

Concentration information loading...

Purity

IgG fraction

Purification notes

Whole antiserum is fractionated and then further purified by ion-exchange chromatography to provide the IgG fraction of antiserum that is essentially free of other rabbit serum proteins.

Clonality

Polyclonal

Isotype

IgG

Applications

Show applications key

Our Abpromise guarantee covers the use of ab50202 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • WB: 1/5000Predicted molecular weight: 54 kDa.(Staining of CaM Kinase IIa in immunoblotting is specifically inhibited with CaM Kinase IIa immunizing peptide. )

  • ShowHide

    IP

     IP: Use at an assay depe...Read more →

    IP: Use at an assay dependent dilution. (5 µg using 10 µg of a synaptosomal fraction of rat brain.)

Target

Function

CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity.

Sequence similarities

Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
Contains 1 protein kinase domain.

Cellular localization

Cell junction > synapse > presynaptic cell membrane. Cell junction > synapse. Postsynaptic lipid rafts.

Target information above from: UniProt accessionQ9UQM7 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • Alpha CaMKII antibody
  • Calcium calmodulin dependent protein kinase II antibody
  • Calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha antibody
  • Calcium/calmodulin-dependent protein kinase II alpha antibody
  • Calcium/calmodulin-dependent protein kinase II-alpha antibody
  • Calcium/calmodulin-dependent protein kinase type II subunit alpha antibody
  • Calcium/calmodulin-dependent protein kinase type IIA antibody
  • CaM kinase II alpha subunit antibody
  • CaM kinase II subunit alpha antibody
  • CaMK II alpha subunit antibody
  • CaMK-II subunit alpha antibody
  • Camk2a antibody
  • CAMKA antibody
  • CaMKII antibody
  • EC 2.7.11.17 antibody
  • KCC2A_HUMAN antibody
  • KIAA0968 antibody
  • MGC123320 antibody
  • MGC139375 antibody
  • MGC155201 antibody
  • mKIAA0968 antibody
  • PK2CDD antibody
  • PKCCD antibody
  • R74975 antibody
  • zgc:112538 antibody
  • zgc:123320 antibody
see all

References for Anti-CaMKII alpha antibody (ab50202)

ab50202 has not yet been referenced specifically in any publications.

Publishing research using ab50202? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"