Anti-CaMKII antibody (ab103840)

Overview

• Product nameAnti-CaMKII antibodySee all CaMKII primary antibodies ...
• Description
  Rabbit polyclonal to CaMKII
• Tested applicationsWB more details
• Species reactivity
  Reacts with: Mouse, Rat
  Predicted to work with: Horse, Chicken, Cow, Dog, Human, Pig, Orangutan
• Immunogen

  Synthetic peptide conjugated to KLH derived from within residues 400 to the C-terminus of Human CaMKII.

  Read Abcam's proprietary immunogen policy

• Positive controlThis antibody gave a positive signal in the following tissue lysates: Mouse brain; Rat brain; Mouse cortex; Rat cortex.

Properties

• FormLiquid
• Storage instructionsStore at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Storage bufferpH: 7.40
  Preservative: 0.02% Sodium azide
  Constituent: PBS
  Note: Batches of this product that have a concentration < 1mg/ml may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help.
• Concentration information loading...
• PurityImmunogen affinity purified
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Metabolism
  • Types of disease
  • Cancer

  • Metabolism
  • Pathways and Processes
  • Metabolism processes
  • Hypoxia

  • Cancer
  • Cancer Metabolism
  • Response to hypoxia

  • Cardiovascular
  • Heart
  • Hypertrophy
  • Other

  • Neuroscience
  • Neurotransmission
  • Calcium Signaling
  • Calmodulin / CaMK

Applications

Target

• FunctionCaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity.
• Sequence similaritiesBelongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
  Contains 1 protein kinase domain.
• Cellular localizationCell junction > synapse > presynaptic cell membrane. Cell junction > synapse. Postsynaptic lipid rafts.

Target information above from: UniProt accession Q9UQM7 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 374174 Chicken
  • Entrez Gene: 374175 Chicken
  • Entrez Gene: 422688 Chicken
  • Entrez Gene: 423737 Chicken
  • Entrez Gene: 530719 Cow
  • Entrez Gene: 525416 Cow
  • Entrez Gene: 532713 Cow
  • Entrez Gene: 282162 Cow

  • Entrez Gene: 816 Human
  • Entrez Gene: 817 Human
  • Entrez Gene: 818 Human
  • Entrez Gene: 815 Human
  • Entrez Gene: 12323 Mouse
  • Entrez Gene: 108058 Mouse
  • Entrez Gene: 12325 Mouse
  • Entrez Gene: 12322 Mouse
  • Entrez Gene: 24246 Rat
  • Entrez Gene: 24245 Rat
  • Entrez Gene: 171140 Rat
  • Entrez Gene: 25400 Rat
  • Omim: 114078 Human
  • SwissProt: Q5ZKI0 Chicken
  • SwissProt: Q3MHJ9 Cow
  • SwissProt: Q2HJF7 Cow
  • SwissProt: Q13554 Human
  • SwissProt: Q13557 Human
  • SwissProt: Q13555 Human
  • SwissProt: Q9UQM7 Human
  • SwissProt: P28652 Mouse
  • SwissProt: Q6PHZ2 Mouse
  • SwissProt: Q923T9 Mouse
  • SwissProt: P11798 Mouse
  • SwissProt: Q95266 Pig
  • SwissProt: P15791 Rat
  • SwissProt: P08413 Rat
  • SwissProt: P11730 Rat
  • SwissProt: P11275 Rat
  • Unigene: 725992 Human
  • Unigene: 131530 Mouse
  • Unigene: 107499 Rat

  see all

• Alternative names
  Calcium/calmodulin dependent protein kinase II alpha antibodyCalcium/calmodulin dependent protein kinase II beta antibodyCalcium/calmodulin dependent protein kinase II delta antibody

  Calcium/calmodulin dependent protein kinase II gamma antibodyCalcium/calmodulin-dependent protein kinase type II subunit alpha antibodyCaM kinase II alpha antibodyCaM kinase II antibodyCaM kinase II beta antibodyCaM kinase II delta antibodyCaM kinase II gamma antibodyCaM kinase II subunit alpha antibodyCaMK-II subunit alpha antibodyCAMK2 antibodyCAMK2A antibodyCAMK2B antibodyCAMK2D antibodyCAMK2G antibodyCAMKA antibodyKCC2A_HUMAN antibody

  see all

Anti-CaMKII antibody images

• 

  Western blot - Anti-CaMKII antibody (ab103840)
  All lanes : Anti-CaMKII antibody (ab103840) at 1 µg/ml
  
  Lane 1 : Brain (Mouse) Tissue Lysate
  Lane 2 : Brain (Rat) Tissue Lysate
  Lane 3 : Mouse cortex Mouse Tissue Lysate
  Lane 4 : Rat Cortex Tissue Lysate
  
  Lysates/proteins at 10 µg per lane.
  
  Secondary
  Goat polyclonal Secondary Antibody to Rabbit IgG - H&L (HRP), pre-adsorbed (ab97080) at 1/5000 dilution
  developed using the ECL technique
  
  Performed under reducing conditions.
  
  Predicted band size : 54 kDa
  Observed band size : 54 kDa
  Additional bands at : 50 kDa (possible isoform).
  
  Exposure time : 1 minute