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Caffeine

Product code: ab120240 (formerly Asc-240)

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Overview

Product name

Caffeine

Description

PDE inhibitor. Adenosine antagonist

Biological description

Psychostimulant. Adenosine A1 and A2A receptor antagonist. Involved in the mobilization of intracellular calcium and the inhibition of cAMP phosphodiesterases.

Purity

> 99%

General notes

Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months.

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Country restrictions and/or license requirements may apply. Please contact customer services for further details.

Properties

Chemical name

1,3,7-Trimethylxanthine

Molecular Weight

194.19

Chemical structure

Chemical Structure

Molecular formula

C8H10N4O2

CAS Number

58-08-2

Solubility

Soluble in water to 100 mM

PubChem identifier

0

Storage instructions

Store at room temperature.

Research areas

Biochemicals >> Research Area >> Stroke >> Adenosine >> Non-selective
Biochemicals >> Research Area >> Respiratory disease >> Adenosine >> Non-selective
Biochemicals >> Research Area >> Heart disease >> Adenosine >> Non-selective
Biochemicals >> Pharmacology >> Receptors & Transporters >> Purinergics >> P1 >> Antagonists
Biochemicals >> Pharmacology >> Receptors & Transporters >> Adenosine >> Non-selective >> Antagonists
Biochemicals >> Pharmacology >> Enzymes >> Phosphodiesterase >> Inhibitors
Biochemicals >> Pharmacology >> Receptors & Transporters >> Adenosine >> Non-selective
Biochemicals >> Chemical Type >> Biochemicals
Biochemicals >> Product Range >> Just Add Water

References for Caffeine (ab120240)

This product has been referenced in:

  • Ferré S An update on the mechanisms of the psychostimulant effects of caffeine. J Neurochem 105:1067-79 (2008).Read more (PubMed: 18088379) »
  • Antoniou K  et al. A detailed behavioral analysis of the acute motor effects of caffeine in the rat: involvement of adenosine A1 and A2A receptors. Psychopharmacology (Berl) 183:154-62 (2005).Read more (PubMed: 16205915) »

See all 3 publications for this product

Publishing research using ab120240? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"