Calcitriol, Vitamin D receptor (VDR) agonist (ab141456)
Key features and details
- Most active form of vitamin D
- CAS Number: 32222-06-3
- Purity: > 99%
- Soluble in DMSO to 100 mM and in ethanol
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Calcitriol, Vitamin D receptor (VDR) agonist -
Description
Most active form of vitamin D -
Purity
> 99% -
General notes
This product is manufactured by BioVision, an Abcam company and was previously called 1880 Calcitriol. 1880-250 is the same size as the 250 µg size of ab141456.
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CAS Number
32222-06-3 -
Chemical structure
Properties
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Chemical name
(1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol -
Molecular weight
416.64 -
Molecular formula
C27H44O3 -
PubChem identifier
5280453 -
Storage instructions
Store at -20°C (desiccating conditions). -
Solubility overview
Soluble in DMSO to 100 mM and in ethanol -
Handling
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(CCCC(C)(C)O)C1CCC2C1(CCCC2=CC=C3CC(CC(C3=C)O)O)C -
Source
Synthetic
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Research areas
- Signal Transduction
- Signaling Pathway
- Nuclear Signaling
- Nuclear Hormone Receptors
- Retinoic & Retinoid
- Signal Transduction
- Signaling Pathway
- Nuclear Signaling
- Nuclear Hormone Receptors
- Vitamin D Receptor
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab141456 has been referenced in 2 publications.
- Patnaik R et al. Efficient Generation of Chondrocytes From Bone Marrow-Derived Mesenchymal Stem Cells in a 3D Culture System: Protocol for a Practical Model for Assessing Anti-Inflammatory Therapies. JMIR Res Protoc 12:e42964 (2023). PubMed: 37505889
- Wu Y et al. The Activation of ROS/NF-?B/MMP-9 Pathway Promotes Calcium-Induced Kidney Crystal Deposition. Oxid Med Cell Longev 2021:8836355 (2021). PubMed: 34211634