Anti-Calneuron 1 antibody (ab117584)
Key features and details
- Rabbit polyclonal to Calneuron 1
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-Calneuron 1 antibody -
Description
Rabbit polyclonal to Calneuron 1 -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat -
Immunogen
Synthetic peptide conjugated to KLH from the N-terminus of Human Calneuron 1
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Positive control
- Human brain cortex tissue
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.4
Preservative: 0.02% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab117584 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
IHC-P |
Use a concentration of 2.5 µg/ml.
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Notes |
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IHC-P
Use a concentration of 2.5 µg/ml. |
Target
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Function
Negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity (By similarity). May play a role in the physiology of neurons and is potentially important in memory and learning. -
Tissue specificity
Brain specific. -
Sequence similarities
Contains 2 EF-hand domains. -
Domain
The C-terminal transmembrane domain (TMD) is necessary and sufficient for membrane targeting. -
Cellular localization
Golgi apparatus, trans-Golgi network membrane. Cytoplasm, perinuclear region. Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 83698 Human
- Entrez Gene: 140904 Mouse
- Entrez Gene: 363909 Rat
- Omim: 607176 Human
- SwissProt: Q9BXU9 Human
- SwissProt: Q9JJG7 Mouse
- SwissProt: Q06BI3 Rat
- Unigene: 592750 Human
see all -
Alternative names
- CaBP8 antibody
- CABP8_HUMAN antibody
- Calcium binding protein 8 antibody
see all
Images
Datasheets and documents
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Datasheet download
References (1)
ab117584 has been referenced in 1 publication.
- Kobuke K et al. Calneuron 1 Increased Ca2+ in the Endoplasmic Reticulum and Aldosterone Production in Aldosterone-Producing Adenoma. Hypertension 71:125-133 (2018). PubMed: 29109191