Overview
- Product nameAnti-Calponin antibodySee all Calponin primary antibodies ...
- DescriptionGoat polyclonal to Calponin
- Tested applicationsIHC-P more details
- Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat, Sheep, Chicken, Cow, Dog, Pig, Ferret - Immunogen
Synthetic peptide: KRQIFEPGLGMEH, corresponding to amino acids 225-237 of Human Calponin (UniProt: P51911).
- Positive controlHuman breast and prostate tissue
Properties
- FormLiquid
- Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
- Storage bufferpH: 7.30
Preservative: 0.02% Sodium azide
Constituents: Tris buffered saline, 0.5% BSA -
Concentration information loading... - PurityImmunogen affinity purified
- Clonality Polyclonal
- IsotypeIgG
- Research Areas
Applications
Our Abpromise guarantee covers the use of ab110128 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Notes |
|---|---|
| IHC-P | IHC-P: Use a concentration of 3 - 6 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
- FunctionThin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.
- Tissue specificitySmooth muscle, and tissues containing significant amounts of smooth muscle.
- Sequence similaritiesBelongs to the calponin family.
Contains 3 calponin-like repeats.
Contains 1 CH (calponin-homology) domain. -
Database links
- Entrez Gene: 396522 Chicken
- Entrez Gene: 534583 Cow
- Entrez Gene: 484937 Dog
- Entrez Gene: 1264 Human
- Entrez Gene: 12797 Mouse
- Entrez Gene: 396911 Pig
- Entrez Gene: 65204 Rat
- Entrez Gene: 443517 Sheep
- Omim: 600806 Human
- SwissProt: P26932 Chicken
- SwissProt: Q2HJ38 Cow
- SwissProt: Q9GK38 Ferret
- SwissProt: P51911 Human
- SwissProt: Q08091 Mouse
- SwissProt: Q08092 Pig
- SwissProt: Q08290 Rat
- SwissProt: Q7YRL2 Sheep
- Unigene: 6630 Cow
- Unigene: 465929 Human
- Unigene: 4356 Mouse
- Unigene: 31788 Rat
- Unigene: 1002 Sheep
see all
Target information above from: UniProt accession
P51911
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010)
.
-
Alternative names
- Basic calponin antibodyCalponin 1 antibodyCalponin 1 basic smooth muscle antibody
- Calponin H1 antibodyCalponin H1 smooth muscle antibodyCalponin-1 antibodyCalponin1 antibodyCalponins basic antibodyCNN 1 antibodyCnn1 antibodyCNN1_HUMAN antibodySm Calp antibodySMCC antibodysmooth muscle antibody
see all
Anti-Calponin antibody images
-
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Calponin antibody (ab110128)Immunohistochemical analysis of formalin fixed, paraffin embedded Human breast tissue labelled with ab110128 at 3 µg/ml. Followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen. -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Calponin antibody (ab110128)Immunohistochemical analysis of formalin fixed, paraffin embedded Human prostate tissue labelled with ab110128 at 3 µg/ml. Followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.
References for Anti-Calponin antibody (ab110128)
ab110128 has not yet been referenced specifically in any publications.
