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Overview

  • Product nameAnti-Calumenin antibodySee all Calumenin primary antibodies ...
  • Description
    Rabbit polyclonal to Calumenin
  • Tested applicationsWB more details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to a region within C terminal amino acids 261-310 (SDYDHAEAEA RHLVYESDQN KDGKLTKEEI VDKYDLFVGS QATDFGEALV) of Human Calumenin (NP_001210).

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI
  • Positive controlU937 cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab118308 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
WB WB: Use a concentration of 1 µg/ml. Predicted molecular weight: 37 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionInvolved in regulation of vitamin K-dependent carboxylation of multiple amino-terminal glutamate residues. Seems to inhibit gamma-carboxylase GGCX. Binds 7 calcium ions with a low affinity.
  • Tissue specificityUbiquitously expressed. Expressed at high levels in heart, placenta and skeletal muscle, at lower levels in lung, kidney and pancreas and at very low levels in brain and liver.
  • Sequence similaritiesBelongs to the CREC family.
    Contains 6 EF-hand domains.
  • Cellular localizationEndoplasmic reticulum lumen. Secreted. Melanosome. Sarcoplasmic reticulum lumen. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

    • Target information above from: UniProt accession O43852 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links
    • Alternative names
        CALU antibodyCALU_HUMAN antibodyCalumenin 1 antibody
        Calumenin 2 antibodyCalumenin antibodyCrocalbin antibodycrocalbin-like protein antibodyFLJ90608 antibodyIEF SSP 9302 antibodymultiple EF-hand protein antibodyOTTHUMP00000212712 antibodyOTTHUMP00000212713 antibodyOTTHUMP00000212714 antibodyOTTHUMP00000212715 antibody
      see all

    Anti-Calumenin antibody images

    • Western blot - Anti-Calumenin antibody (ab118308)
      Western blot - Anti-Calumenin antibody (ab118308)
      Anti-Calumenin antibody (ab118308) at 1 µg/ml + U937 cell lysate at 10 µg

      Predicted band size : 37 kDa

    References for Anti-Calumenin antibody (ab118308)

    ab118308 has not yet been referenced specifically in any publications.

    Publishing research using ab118308 ? Please let us know so that we can cite the reference in this datasheet

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