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Product name
Camptothecin
Description
DNA topoisomerase inhibitor
Biological description
Cell permeable DNA topoisomerase inhibitor. Potent anti-tumour and antibiotic agent.
Purity
> 98%
General notes
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Country restrictions and/or license requirements may apply. Please contact customer services for further details.
Properties
Chemical name
(S)-4-Ethyl-4-hydroxy-1H-pyrano-[3'4':6,7] indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
Molecular Weight
348.35
Chemical structure
Molecular formula
C20H16N2O4
CAS Number
7689-03-4
Solubility
Soluble in DMSO to 5 mM
Storage instructions
Store at +4°C (desiccating conditions). Do not freeze.
Research areas
Biochemicals >> Pharmacology >> Enzymes >> Isomerase >> General >> Inhibitors
Biochemicals >> Chemical Type >> Biochemicals
References for Camptothecin (ab120115)
This product has been referenced in:
- Capranico G et al. The effects of camptothecin on RNA polymerase II transcription: roles of DNA topoisomerase I. Biochimie 89:482-9 (2007).Read more (PubMed: 17336444) »
- Li QY et al. Review camptothecin: current perspectives. Curr Med Chem 13:2021-39 (2006).Read more (PubMed: 16842195) »
See all 3 publications for this product
Publishing research using ab120115? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"