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Cancer Antigen CA15-3 Human ELISA Kit (ab108633)

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Overview

  • Product nameCancer Antigen CA15-3 Human ELISA Kit
  • Detection methodColorimetric
  • Tests
    1 x 96 well plate
  • Sample type
    Serum
  • Assay typeSandwich
  • Sensitivity
    = 5 U/ml
  • Range
    5 U/ml - 240 U/ml
  • Assay durationMultiple steps standard assay
  • Species reactivity
    Reacts with: Human
  • Product overview

    ab108633 Cancer Antigen CA15-3 Human ELISA Kit is intended for the quantitative determination of the Cancer Antigen CA15-3 concentration in human serum.

    Breast cancer is the most common life-threatening malignant lesion in women of many developed countries today, with approximately 180,000 new cases diagnosed every year.

    There are a number of tumor markers that can help clinicians to identify and diagnose which breast cancer patients will have aggressive disease and which will have an indolent course. These markers include estrogen and progesterone receptors, DNA ploidy and percent-S phase profile, epidermal growth factor receptor, HER-2/neu oncogene, p53 tumor suppressor gene, cathepsin D, proliferation markers and CA15-3. CA15-3 is most useful for monitoring patients post-operatively for recurrence, particularly metastatic diseases. 96% of patients with local and systemic recurrence have elevated CA15-3, which can be used to predict recurrence earlier than radiological and clinical criteria. A 25% increase in the serum CA15-3 is associated with progression of carcinoma. A 50% decrease in serum CA15-3 is associated with response to treatment. CA15-3 is more sensitive than CEA in early detection of breast cancer recurrence.

  • Tested applicationsSandwich ELISA more details
  • PlatformMicroplate

Properties

  • Alternative names
      CA15-3Cancer Antigen CA15-3

Applications

Our Abpromise guarantee covers the use of ab108633 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
Sandwich ELISA sELISA

Cancer Antigen CA15-3 Human ELISA Kit images

  • - Cancer Antigen CA15-3 Human ELISA Kit (ab108633)
    - Cancer Antigen CA15-3 Human ELISA Kit (ab108633)

Protocols

References for Cancer Antigen CA15-3 Human ELISA Kit (ab108633)

ab108633 has not yet been referenced specifically in any publications.

Publishing research using ab108633 ? Please let us know so that we can cite the reference in this datasheet

Product Wall

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Regarding the CA15-3 elisa kit: the standard solutions are in U/ml. MUC1 protein that you provide is mg/ml. In case we use your protein for an immunoassay and your kit as a reference method is there a possibility to convert mg/ml in U/ml? do yo...

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We recieved an answer from the collaborating lab regarding your question:

"We purchased at least 100 CA15-3 patient samples from a vendor(s). The vendor provided us the CA15-3 value for each sample tested by Abbott's CA15-3 test. We then t...

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Can the kit be used to detect recombinant CA15-3?

Unfortunately, we have not tested this kit with recombinant CA15-3 and therefore have no information as to whether it will work with a recombinant protein. This also means that this product would not be covered by our abpromise guarantee if used with reco...

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Inquiry: Hi I'm student from MOROCCO I've already asked you about Elisa kits for HER2 AND CA15-3 proteins detection our supplier told us that he already order those kits from your laboratory and now we need Elisa kits for detection of antibodies anti-HER2...

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Thank you for your inquiry.

I am sorry to confirm that we do not have any ELISA kits to detect anti-HER2 and anti-CA15-3 antibodies.

If I understand correctly, you would like to detect the actual antibodies from serum etc? There is the...

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what does 1 U/ml of the standard corresponds to in mg/ml?

Thank you for your patience.

This is the additional information I received from the supplying lab:

We purchased at least 100 CA15-3 patient samples from a vendor. The vendor provided us the CA15-3 value for each sample tested by Abbo...

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what does 1 U/ml of the standard corresponds to in mg/ml?

Thank you for contacting us.

I have received this information from the lab so far:
There is no WHO standard or international standard for this product. We calibrate the CA15-3 kit against the Abbott's test.

I have inquired about ...

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 Dear technical team,   Our customer would like to purchase these kits and wants to know the meaning of "unit"  in Sensitivity : 5U/ml.   1. unit definition   2. is it possible conversion of unit  to  ng?   Check this please.     Best regards,

Thank you for your enquiry. I can confirm that this kit is sourced externally. They have kindly provided the following information: 1. When this kit was first designed, the antigens used were not pure.  So the antigen concentrations was expressed in U/ml....

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"