Cancer Antigen CA15-3 Human ELISA Kit (ab108633)

Overview

  • Product nameCancer Antigen CA15-3 Human ELISA Kit
  • Detection methodColorimetric
  • Tests
    1 x 96 well plate
  • Sample type
    Serum
  • Assay typeSandwich (quantitative)
  • Sensitivity
    = 5 U/ml
  • Range
    5 U/ml - 240 U/ml
  • Assay durationMultiple steps standard assay
  • Species reactivity
    Reacts with: Human
  • Product overview

    ab108633 Cancer Antigen CA15-3 Human ELISA Kit is intended for the quantitative determination of the Cancer Antigen CA15-3 concentration in human serum.

    Breast cancer is the most common life-threatening malignant lesion in women of many developed countries today, with approximately 180,000 new cases diagnosed every year.

    There are a number of tumor markers that can help clinicians to identify and diagnose which breast cancer patients will have aggressive disease and which will have an indolent course. These markers include estrogen and progesterone receptors, DNA ploidy and percent-S phase profile, epidermal growth factor receptor, HER-2/neu oncogene, p53 tumor suppressor gene, cathepsin D, proliferation markers and CA15-3. CA15-3 is most useful for monitoring patients post-operatively for recurrence, particularly metastatic diseases. 96% of patients with local and systemic recurrence have elevated CA15-3, which can be used to predict recurrence earlier than radiological and clinical criteria. A 25% increase in the serum CA15-3 is associated with progression of carcinoma. A 50% decrease in serum CA15-3 is associated with response to treatment. CA15-3 is more sensitive than CEA in early detection of breast cancer recurrence.

  • Tested applicationsSandwich ELISA more details
  • PlatformMicroplate

Properties

  • Alternative names
    • CA15-3
    • Cancer Antigen CA15-3

Applications

Our Abpromise guarantee covers the use of ab108633 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
Sandwich ELISA Use at an assay dependent dilution.

Cancer Antigen CA15-3 Human ELISA Kit images

Protocols

References for Cancer Antigen CA15-3 Human ELISA Kit (ab108633)

ab108633 has not yet been referenced specifically in any publications.

Product Wall

We recieved an answer from the collaborating lab regarding your question:

"We purchased at least 100 CA15-3 patient samples from a vendor(s). The vendor provided us the CA15-3 value for each sample tested by Abbott's CA15-3 test. We the...

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Unfortunately, we have not tested this kit with recombinant CA15-3 and therefore have no information as to whether it will work with a recombinant protein. This also means that this product would not be covered by our abpromise guarantee if used with r...

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Thank you for your inquiry.

I am sorry to confirm that we do not have any ELISA kits to detect anti-HER2 and anti-CA15-3 antibodies.

If I understand correctly, you would like to detect the actual antibodies from serum etc? There is ...

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Thank you for your patience.

This is the additional information I received from the supplying lab:

We purchased at least 100 CA15-3 patient samples from a vendor. The vendor provided us the CA15-3 value for each sample tested by A...

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Thank you for contacting us.

I have received this information from the lab so far:
There is no WHO standard or international standard for this product. We calibrate the CA15-3 kit against the Abbott's test.

I have inquired abo...

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Thank you for your enquiry. I can confirm that this kit is sourced externally. They have kindly provided the following information: 1. When this kit was first designed, the antigens used were not pure.  So the antigen concentrations was expressed in U/...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"