Loading...
You have changed your country from
to
. Please be aware that this will change the currency in the purchasing process.
Products:Neuroscience >> Sensory System >> Visual system
Overview
Product name
Anti-Carbonic Anhydrase IV antibody
See all Carbonic Anhydrase IV products (3) ...
Description
Mouse polyclonal to Carbonic Anhydrase IV
Tested applications
Cross reactivity
Reacts with
Human
Immunogen
Full length Human Carbonic Anhydrase IV (NP_000708.1, amino acids 1-312).
Positive control
A-431 cell lysate, Carbonic Anhydrase IV transfected 293T cell lysate.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: 1X PBS, pH 7.2
Concentration
Concentration information loading...
Purity
Protein A purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Applications
Show applications key
Our Abpromise guarantee covers the use of ab89610 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use a concentration of 1 µg/mlPredicted molecular weight: 35 kDa.
Target
Relevance
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. Carbonic Anhydrase IV is a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary (and certain other) capillaries and of proximal renal tubules which may have a role in inherited renal abnormalities of bicarbonate transport.
Cellular localization
Cell membrane; Lipid-anchor, GPI-anchor.
Alternative names
- CA IV antibody
- CAIV antibody
- Car4 antibody
see all
Database links
- Entrez Gene: 762 Human
- GenBank: NM_000717 Human
- Omim: 114760 Human
- SwissProt: P22748 Human
- Unigene: 89485 Human
Anti-Carbonic Anhydrase IV antibody images:
Western blot - Carbonic Anhydrase IV antibody (ab89610)
Anti-Carbonic Anhydrase IV antibody (ab89610) at 1 µg/ml + A-431 cell lysate at 50 µg
Predicted band size : 35 kDa
Observed band size : 35 kDa
Western blot - Carbonic Anhydrase IV antibody (ab89610)
All lanes : Anti-Carbonic Anhydrase IV antibody (ab89610) at 1 µg/ml
Lane 1 : Carbonic Anhydrase IV transfected 293T cell lysate
Lane 2 : Non-transfected 293T cell lysate
Lysates/proteins at 25 µg per lane.
Predicted band size : 35 kDa
Observed band size : 32 kDa (why is the actual band size different from the predicted?)
References for Anti-Carbonic Anhydrase IV antibody (ab89610)
ab89610 has not yet been referenced specifically in any publications.
Publishing research using ab89610? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"