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Anti-Carboxypeptidase M antibody [1C2] (ab49278)

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Overview

Product name

Anti-Carboxypeptidase M antibody [1C2]
See all Carboxypeptidase M products (3) ...

Description

Mouse monoclonal [1C2] to Carboxypeptidase M

Tested applications

IHC-Fr, IHC-Pmore details

Cross reactivity

Reacts with

Human

Immunogen

Recombinant prokaryotic carboxypeptidase M purified by ion-exchange and affinity chromatography.

Positive control

Placenta

Properties

Form

Lyophilised:
Reconstitute with the volume of sterile distilled water indicated on the vial label.

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Storage buffer

Preservative: 15mM Sodium Azide
Constituents: Tissue culture supernatant

Concentration

Concentration information loading...

Purity

Tissue culture supernatant

Clonality

Monoclonal

Clone number

1C2

Myeloma

P3-NS1/1-Ag4-1

Isotype

IgG1

Light chain type

kappa

Research areas

Signal Transduction >> Growth Factors/Hormones >> Hormones
Immunology >> Innate Immunity >> Macrophage / Inflamm.

Applications

Show applications key

Our Abpromise guarantee covers the use of ab49278 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • IHC-Fr

     

  • IHC-P

     

Application notes

IHC-Fr: 1/200 - 1/400.
IHC-P: 1/20 - 1/40. High temperature antigen unmasking technique is recommended.
Use 60 minutes primary antibody incubation at 25oC followed by standard ABC technique.

Is unsuitable for WB.


Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Target

Function

Specifically removes C-terminal basic residues (Arg or Lys) from peptides and proteins. It is believed to play important roles in the control of peptide hormone and growth factor activity at the cell surface, and in the membrane-localized degradation of extracellular proteins.

Sequence similarities

Belongs to the peptidase M14 family.

Cellular localization

Cell membrane.

Target information above from: UniProt accessionP14384 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • Carboxypeptidase M antibody
  • CBPM_HUMAN antibody
  • CPM antibody

Database links

References for Anti-Carboxypeptidase M antibody [1C2] (ab49278)

ab49278 has not yet been referenced specifically in any publications.

Publishing research using ab49278? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"