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- Primary antibodies
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Product name
Caspase 2 peptide
See all Caspase 2 products (3) ...
Protein description
Synthetic peptide, corresponding to the N-Terminus of Human Caspase 2.
Properties
Purification notes
ab39724 is a crude synthetic peptide, purity range from 60-80%. The sequence is proprietary.
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer
Preservative: 0.02% Sodium Azide
Constituents: 0.1% BSA, PBS, pH 7.2
Concentration
Concentration information loading...
Research areas
Metabolism >> Pathways and Processes >> Metabolism processes >> Apoptosis
Cell Biology >> Proteolysis / Ubiquitin >> Proteolytic enzymes >> Other proteases
Cancer >> Invasion/microenvironment >> Apoptosis >> Caspases
Cell Biology >> Apoptosis >> Intracellular >> Caspases etc >> Caspases
Applications
Show applications key
Our Abpromise guarantee covers the use of ab39724 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB
Application notes
WB: Use at an assay dependent dilution. Predicted molecular weight: 49 kDa.
This peptide can be used with studies using ab25896.
Incubating the peptide with equal volume of antibody for 30 min at 37°C usually blocks the antibody activity completely in Western blot analysis.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Protein info
Function
Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.
Tissue specificity
Expressed at higher levels in the embryonic lung, liver and kidney than in the heart and brain. In adults, higher level expression is seen in the placenta, lung, kidney, and pancreas than in the heart, brain, liver and skeletal muscle.
Sequence similarities
Belongs to the peptidase C14A family.
Contains 1 CARD domain.
Post-translational
modifications
The mature protease can process its own propeptide, but not that of other caspases.
Target information above from: UniProt accessionP42575
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
References for Caspase 2 peptide (ab39724)
ab39724 has not yet been referenced specifically in any publications.
Publishing research using ab39724? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"