Overview

  • Product name
  • Description
    Rabbit polyclonal to Catalase
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Zebrafish
  • Immunogen

    Recombinant fragment within Zebrafish Catalase aa 109-361. The exact sequence is proprietary.
    Sequence:

    IV VRFSTVAGEA GSPDTVRDPR GFAVKFYTDE GNWDLTGNNT PTFFIRDTLL SPSFIHSQKR NPQTHLKDPD MVWDFWSLRP ESLHQVSFLF SDRGIPDGYR HMNGYGSHTF KLVNAQGQPV YCKFHYKTNQ GIKNIPVEEA DRLAATDPDY SIRDLYNAIA NGNFPSWTFY IQVMTFEQAE NWKWNPFDLT KVWSHKEFPL IPVGRFVLNR NPVNYFAEVE QLAFDPSNMP PGIEPSPDKM LQGRLFSYPD T


    Database link: Q9PT92

  • Positive control
    • IHC-P: Zebrafish tissue. WB: Zebrafish muscle whole tissue lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab209721 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 60 kDa.
IHC-P 1/100 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells.
  • Involvement in disease
    Defects in CAT are the cause of acatalasia (ACATLAS) [MIM:115500]; also known as acatalasemia. This disease is characterized by absence of catalase activity in red cells and is often associated with ulcerating oral lesions.
  • Sequence similarities
    Belongs to the catalase family.
  • Post-translational
    modifications
    The N-terminus is blocked.
  • Cellular localization
    Peroxisome.
  • Information by UniProt
  • Database links
    • Alternative names
      • Cas1 antibody
      • CAT antibody
      • CATA_HUMAN antibody
      • Catalase antibody
      • Cs1 antibody
      • MGC138422 antibody
      • MGC138424 antibody
      see all

    Images

    • Immunohistochemical analysis of paraffin-embedded Zebrafish tissue labeling Cat with ab209721 at 1/300 dilution.

    • Anti-Catalase antibody (ab209721) at 1/1000 dilution + Zebrafish muscle whole cell lysate at 30 µg

      Predicted band size: 60 kDa



      7.5% SDS PAGE

    References

    ab209721 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab209721.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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