![Western blot - Cathelicidin antibody [mAbcam 58387] (ab58387) image](#Cathelicidin-Primary-antibodies-ab58387-1.jpg)
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Products:Microbiology >> Lipopolysaccharide >> Bacterial Lipopolysaccharide
Overview
Product name
Anti-Cathelicidin antibody [mAbcam 58387]
See all Cathelicidin products (14) ...
Description
Mouse monoclonal [mAbcam 58387] to Cathelicidin
Tested applications
Cross reactivity
Reacts with
Human
Predicted to work with
Chimpanzee, Gorilla, Orangutan
Immunogen
Synthetic peptide conjugated to KLH derived from within residues 150 to the C-terminus of Human Cathelicidin.
Positive control
This antibody gave a positive signal in human spleen tissue lysate.
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 0.02% Sodium Azide
Constituents: 1% BSA, PBS, pH 7.4
Concentration
Concentration information loading...
Purity
IgG fraction
Primary antibody notes
CAP18 is the only human cathelicidin found so far and closely resembles CRAMP, the sole member of this gene family in mice. LL-37 is the 37 amino acid C-terminal antibacterial protein.
Clonality
Monoclonal
Clone number
mAbcam 58387
Myeloma
Sp2/0-Ag14
Isotype
IgG
Research areas
Immunology >> Secreted Molecules >> Other secreted molecules
Microbiology >> Lipopolysaccharide >> Bacterial Lipopolysaccharide
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Western blot - Cathelicidin antibody [mAbcam 58387] (ab58387)
![Western blot - Cathelicidin antibody [mAbcam 58387] (ab58387) image](/ps/datasheet/images/58/ab58387/Cathelicidin-Primary-antibodies-ab58387-1.jpg)
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Applications
Show applications key
Our Abpromise guarantee covers the use of ab58387 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use a concentration of 10 µg/mlDetects a band of approximately 19 kDa (predicted molecular weight: 19 kDa).
Target
Function
Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity.
Tissue specificity
Expressed in bone marrow and testis and neutrophils.
Sequence similarities
Belongs to the cathelicidin family.
Post-translational
modifications
The N-terminus is blocked.
Cellular localization
Secreted.
Target information above from: UniProt accessionP49913
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- 18 kDa cationic antimicrobial protein antibody
- Antibacterial protein FALL-39 antibody
- Antibacterial protein LL-37 antibody
see all
Database links
- Entrez Gene: 12796 Human
- Entrez Gene: 820 Human
- Omim: 600474 Human
- SwissProt: P49913 Human
- Unigene: 51120 Human
Anti-Cathelicidin antibody [mAbcam 58387] images:
Western blot - Cathelicidin antibody [mAbcam 58387] (ab58387)
Anti-Cathelicidin antibody [mAbcam 58387] (ab58387) at 10 µg/ml + Spleen (Human) Tissue Lysate - adult normal tissue (ab29699) at 20 µg
Secondary
Mouse IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution
developed using the ECL technique
Performed under reducing conditions.
Predicted band size : 19 kDa
Observed band size : 19 kDa
Additional bands at : 60 kDa. We are unsure as to the identity of these extra bands.
Exposure time : 30 seconds
References for Anti-Cathelicidin antibody [mAbcam 58387] (ab58387)
ab58387 has not yet been referenced specifically in any publications.
Publishing research using ab58387? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"