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Immunohistochemistry (Paraffin-embedded sections) - Cathepsin G antibody [19C3] (ab50845)
Immunohistochemistry (Paraffin-embedded sections) - Cathepsin G antibody [19C3] (ab50845)
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Product Name 

Cathepsin G antibody [19C3]

 

See all Cathepsin G antibodies (12)...

Product type 

Primary antibodies

Description 

Mouse monoclonal [19C3] to Cathepsin G

Immunogen 

Prokaryotic recombinant protein corresponding to a 124 amino acid N-terminal region of the cathepsin G molecule.

Reacts with 
(species key)

Hu

Specificity 

ab50845 is specific to human Cathepsin G.

Tested applications 
(see key)

IHC-P, WB


Abreviews 

Customer reviews
(see key)


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Application notes 
(see key)

Recommended dilutions
IHC-P: 1/100 - 1/200. (Use high temperature antigen unmasking).
WB: 1/50. Predicted molecular weight: 29 kDa.


Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Positive control 
(see definition)

Human PBL cell line and human tonsil tissue.

Cellular localization 

Cell surface

Research areas 

Signal Transduction >> Cytoskeleton / ECM >> Extracellular Matrix >> ECM Enzymes >> Other Enzymes
Neuroscience >> Cell Adhesion Proteins >> Membrane Proteins

Relevance 

Cathepsin G is a serine protease, consisting of a single polypeptide with a molecular weight of 30 kDa as determined by SDS-PAGE. Its substrates are collagen and proteoglycans. Poor regulation of Cathepsin G levels has been associated with various connective tissue disorders, for example pulmonary emphysema and cystic fibrosis.

 

Alternative names Cathepsin G antibody [19C3] (ab50845)

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

1511    (Human)

Omim

    

116830    (Human)

SwissProt

    

P08311    (Human)

Raised in 

Mouse

Clonality 

Monoclonal

Clone number 

19C3

Myeloma 

P3-NS1/1-Ag4-1

Isotype 

IgG1

Purity 

Tissue culture supernatant

Storage buffer 

Preservative: 15mM Sodium Azide
Constituents: Tissue culture supernatant

Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS

Form 

Liquid

Concentration 

Concentration not determined - why is this?

Storage instructions 

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

 

At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Cathepsin G antibody [19C3] is on this datasheet. But please do contact us if you would like any reassurance!


See below for Cathepsin G antibody [19C3] images, references, products related to ab50845 and other tools.

 

Cathepsin G antibody [19C3] images:

Product image  Immunohistochemistry (Paraffin-embedded sections) - Cathepsin G antibody [19C3] (ab50845)

Immunohistochemistry (Paraffin-embedded sections) - Cathepsin G antibody [19C3] (ab50845)

Immunohistochemical staining for Cathepsin G using ab50845 (1/100 dilution) in tonsil tissue. Note intense membrane staining of polymorphonuclear leukocytes. Paraffin section.

 
 

Search PubMed (MEDLINE) for references to Cathepsin G

 

Cathepsin G antibody [19C3] - more information

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