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Anti-Cathepsin G antibody [19C3] (ab50845)

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Overview

Product name

Anti-Cathepsin G antibody [19C3]
See all Cathepsin G products (12) ...

Description

Mouse monoclonal [19C3] to Cathepsin G

Specificity

ab50845 is specific to human Cathepsin G.

Tested applications

WB, IHC-Pmore details

Cross reactivity

Reacts with

Human

Immunogen

Prokaryotic recombinant protein corresponding to a 124 amino acid N-terminal region of the cathepsin G molecule.

Positive control

Human PBL cell line and human tonsil tissue.

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Storage buffer

Preservative: 15mM Sodium Azide
Constituents: Tissue culture supernatant

Purity

Tissue culture supernatant

Clonality

Monoclonal

Clone number

19C3

Myeloma

P3-NS1/1-Ag4-1

Isotype

IgG1

Research areas

Signal Transduction >> Cytoskeleton / ECM >> Extracellular Matrix >> ECM Enzymes >> Other Enzymes
Neuroscience >> Cell Adhesion Proteins >> Membrane Proteins

  • Immunohistochemistry (Paraffin-embedded sections) - Cathepsin G antibody [19C3] (ab50845)Immunohistochemistry (Paraffin-embedded sections) - Cathepsin G antibody [19C3] (ab50845) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab50845 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Target

Function

Serine protease with trypsin- and chymotrypsin-like specificity. Cleaves complement C3. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa, antibacterial activity is inhibited by LPS from P.aeruginosa, Z-Gly-Leu-Phe-CH2Cl and phenylmethylsulfonyl fluoride.

Sequence similarities

Belongs to the peptidase S1 family.
Contains 1 peptidase S1 domain.

Cellular localization

Cell surface.

Target information above from: UniProt accessionP08311 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • CATG antibody
  • CATG_HUMAN antibody
  • Cathepsin G antibody
  • Cathepsin G precursor antibody
  • CathepsinG antibody
  • CG antibody
  • CTSG antibody
  • CTSG protein antibody
  • MGC23078 antibody
see all

Database links

Anti-Cathepsin G antibody [19C3] images:

  Immunohistochemistry (Paraffin-embedded sections) - Cathepsin G antibody [19C3] (ab50845)

Immunohistochemistry (Paraffin-embedded sections) - Cathepsin G antibody [19C3] (ab50845)

Immunohistochemical staining for Cathepsin G using ab50845 (1/100 dilution) in tonsil tissue. Note intense membrane staining of polymorphonuclear leukocytes. Paraffin section.

References for Anti-Cathepsin G antibody [19C3] (ab50845)

This product has been referenced in:

  • Zoega Met al. Proteinase 3 carries small unusual carbohydrates and associates with alpha-defensins. J Proteomics : (2011).Read more (PubMed: 22138257) »
  • Reece STet al. Serine protease activity contributes to control of Mycobacterium tuberculosis in hypoxic lung granulomas in mice. J Clin Invest 120:3365-76 (2010). IHC-P; Mouse.Read more (PubMed: 20679732) »

See all 3 publications for this product

Publishing research using ab50845? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"