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Anti-Cathepsin G antibody (ab8816)

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Overview

Product name

Anti-Cathepsin G antibody
See all Cathepsin G products (12) ...

Description

Sheep polyclonal to Cathepsin G

Specificity

This product gives a single arc when tested by IEP and 2D-IEP against human Cathepsin G. Identity isconfirmed by double diffusion (Ouchterlony) verses human Cathepsin G and a known anti-humanCathepsin G.

Tested applications

WBmore details

Cross reactivity

Reacts with

Human

Immunogen

Human Cathepsin G purified from human neutrophils. Greater than 95% pure by SDS-PAGE.

Properties

Form

Liquid

Storage instructions

Store at +4°C.

Storage buffer

Glycine buffered saline pH7.4, 0.1% Sodium Azide, 0.1% EACA, 0.01% Benzamidine,1mM EDTA

Concentration

Concentration information loading...

Purity

IgG fraction

Clonality

Polyclonal

Myeloma

unknown

Isotype

IgG

Light chain type

unknown

Research areas

Signal Transduction >> Cytoskeleton / ECM >> Extracellular Matrix >> ECM Enzymes >> Other Enzymes
Neuroscience >> Cell Adhesion Proteins >> Membrane Proteins

Applications

Show applications key

Our Abpromise guarantee covers the use of ab8816 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

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    WB

     WB: 1/500(Suitability fo...Read more →

    WB: 1/500(Suitability for use in nephelometry, immunohistochemical procedures and enzyme-linked immunosorbent assays has not been assessed but use in such assays should not necessarily be excluded.)

Target

Function

Serine protease with trypsin- and chymotrypsin-like specificity. Cleaves complement C3. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa, antibacterial activity is inhibited by LPS from P.aeruginosa, Z-Gly-Leu-Phe-CH2Cl and phenylmethylsulfonyl fluoride.

Sequence similarities

Belongs to the peptidase S1 family.
Contains 1 peptidase S1 domain.

Cellular localization

Cell surface.

Target information above from: UniProt accessionP08311 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • CATG antibody
  • CATG_HUMAN antibody
  • Cathepsin G antibody
  • Cathepsin G precursor antibody
  • CathepsinG antibody
  • CG antibody
  • CTSG antibody
  • CTSG protein antibody
  • MGC23078 antibody
see all

Database links

References for Anti-Cathepsin G antibody (ab8816)

This product has been referenced in:

  • Prince LRet al. Subversion of a lysosomal pathway regulating neutrophil apoptosis by a major bacterial toxin, pyocyanin. J Immunol 180:3502-11 (2008). WB.Read more (PubMed: 18292577) »
  • Dick EPet al. Ex vivo-expanded bone marrow CD34+ derived neutrophils have limited bactericidal ability. Stem Cells 26:2552-63 (2008). WB; Human.Read more (PubMed: 18669908) »

See all 2 publications for this product

Publishing research using ab8816? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"