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Products:Immunology >> Adaptive Immunity >> MHC >> Class II
Overview
Product name
Cathepsin S peptide
See all Cathepsin S products (5) ...
Protein description
This peptide was used as an immunogen for ab18822 - Cathepsin S antibody.
Properties
Purity
>90% by SDS-PAGE
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 0.02% Thimerosal (merthiolate)
Constituents: 0.1% BSA, PBS, pH 7.2
Concentration
Concentration information loading...
Research areas
Cell Biology >> Proteolysis / Ubiquitin >> Proteolytic enzymes >> Cysteine protease >> Cathepsins
Cell Biology >> Proteolysis / Ubiquitin >> Proteolytic enzymes
Immunology >> Cell Type Markers >> Non-CD >> APC
Tags & Cell Markers >> Subcellular Markers >> Organelles >> Lysosome
Immunology >> Adaptive Immunity >> MHC >> Class II
Applications
Show applications key
Our Abpromise guarantee covers the use of ab54080 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB
Application notes
WB: Use at an assay dependent dilution.
This peptide can be used with studies using ab18822.
ab54080 blocks antibody activity completely in Western blot analysis by incubating the
peptide with equal volume of antibody for 30 minutes at 37°C
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Protein info
Relevance
Cathepsin family of proteases contains several diverse classes of enzymes. The cysteine protease class comprises cathepsin B, H, K, L, O, and S. The aspartyl protease class contains cathepsin D and E. Cathepsin G belongs to the serine protease class. Cathepsins are involved in various cellular events such as peptide biosynthesis, protein degradation, and apoptosis. Cathepsin S has been shown to be able to function as an elastase over a broad pH range in alveolar macrophages. Transcript variants utilizing alternative polyadenylation signals exist for this gene.
Cellular localization
Lysosomal.
References for Cathepsin S peptide (ab54080)
ab54080 has not yet been referenced specifically in any publications.
Publishing research using ab54080? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"