Overview

  • Product name
    Anti-Cdk2 antibody [SP80]
    See all Cdk2 primary antibodies
  • Description
    Rabbit monoclonal [SP80] to Cdk2
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    A synthetic peptide corresponding to the C-terminal region of Human Cdk2 protein.

  • Positive control
    • Human tonsil
  • General notes

     

     

    This product is a recombinant rabbit monoclonal antibody.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab101682 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/50. Predicted molecular weight: 34 kDa. for 1 hour at RT.
IHC-P 1/100. Incubate for 30 minutes at RT. Antigen retrieval is recommended: boil tissue section in 1mM EDTA, pH 8.0 for 10 min followed by cooling at RT for 20 min.

Target

  • Function
    Involved in the control of the cell cycle. Interacts with cyclins A, B1, B3, D, or E. Activity of CDK2 is maximal during S phase and G2.
  • Sequence similarities
    Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
    Contains 1 protein kinase domain.
  • Information by UniProt
  • Database links
  • Alternative names
    • Cdc2 related protein kinase antibody
    • cdc2-related protein kinase antibody
    • CDC28 antibody
    • CDC2A antibody
    • Cdk 2 antibody
    • CDK1 antibody
    • CDK2 antibody
    • CDK2_HUMAN antibody
    • CDKN2 antibody
    • Cell devision kinase 2 antibody
    • Cell division protein kinase 2 antibody
    • Cyclin dependent kinase 2 antibody
    • cyclin dependent kinase 2-alpha antibody
    • Cyclin-dependent kinase 2 antibody
    • kinase Cdc2 antibody
    • MPF antibody
    • p33 protein kinase antibody
    • p33(CDK2) antibody
    see all

Images

  • Immunohistochemical analysis of Cdk2 expression in formalin-fixed, paraffin-embedded Human tonsil using ab101682 at 1/100 dilution.
  • Anti-Cdk2 antibody [SP80] (ab101682) at 1/100 dilution + lysate prepared from HeLa cells

    Predicted band size: 34 kDa
    Observed band size: 33 kDa (why is the actual band size different from the predicted?)

References

This product has been referenced in:
  • Qi H  et al. Activation of AMPK Attenuated Cardiac Fibrosis by Inhibiting CDK2 via p21/p27 and miR-29 Family Pathways in Rats. Mol Ther Nucleic Acids 8:277-290 (2017). Read more (PubMed: 28918029) »

See 1 Publication for this product

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab101682.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up