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Anti-Cdk5 antibody [2G2] (ab28441)

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Overview

Product name

Anti-Cdk5 antibody [2G2]
See all Cdk5 products (15) ...

Description

Mouse monoclonal [2G2] to Cdk5

Tested applications

ELISA, WB, IP, Sandwich ELISAmore details

Cross reactivity

Reacts with

Mouse, Rat, Human

Immunogen

His-tagged recombinant human CDK5 protein purified from E. coli

Positive control

SH-SY5Y cell lysate

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Storage buffer

Preservative: 0.03% Proprietary Preservative
Constituents: 50% Glycerol, 0.01% BSA, HEPES, 0.15M Sodium chloride

Concentration

Concentration information loading...

Purity

IgG fraction

Clonality

Monoclonal

Clone number

2G2

Isotype

IgG1

Light chain type

kappa

Research areas

Cancer >> Cell cycle >> Cell division
Neuroscience >> Neurology process >> Neurogenesis
Cell Biology >> Cell Cycle >> Kinases/Phosphatases >> Cdks

  • Sandwich ELISA - Cdk5 antibody [2G2] (ab28441)Sandwich ELISA - Cdk5 antibody [2G2] (ab28441) image (enlarge)

  • Western blot - Cdk5 antibody [2G2] (ab28441)Western blot - Cdk5 antibody [2G2] (ab28441) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab28441 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Target

Function

Probably involved in the control of the cell cycle. Interacts with D1 and D3-type G1 cyclins. Can phosphorylate histone H1, tau, MAP2 and NF-H and NF-M. Also interacts with p35 which activates the kinase.

Sequence similarities

Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
Contains 1 protein kinase domain.

Cellular localization

Cytoplasm. Cell projection > lamellipodium. Cell projection > growth cone. In axonal growth cone with extension to the peripheral lamellipodia.

Target information above from: UniProt accessionQ00535 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • Cdk 5 antibody
  • Cdk5 antibody
  • CDK5_HUMAN antibody
  • Cell division protein kinase 5 antibody
  • Crk6 antibody
  • Cyclin dependent kinase 5 antibody
  • Cyclin-dependent kinase 5 antibody
  • Protein kinase CDK5 splicing antibody
  • PSSALRE antibody
  • Serine threonine protein kinase PSSALRE antibody
  • Serine/threonine-protein kinase PSSALRE antibody
  • Tau protein kinase II catalytic subunit antibody
  • TPKII catalytic subunit antibody
see all

Database links

see all

Anti-Cdk5 antibody [2G2] images:

  Sandwich ELISA - Cdk5 antibody [2G2] (ab28441)

Sandwich ELISA - Cdk5 antibody [2G2] (ab28441)

Standard Curve for Cdk5 (Analyte: Cdk5 protein (Tagged) (ab56282)); dilution range 1pg/ml to 1µg/ml using Capture Antibody Mouse monoclonal [2G2] to Cdk5 (ab28441) at 5µg/ml and Detector Antibody Rabbit polyclonal to Cdk5 (ab21249) at 0.5µg/ml.

  Western blot - Cdk5 antibody [2G2] (ab28441)

Western blot - Cdk5 antibody [2G2] (ab28441)

All lanes : Anti-Cdk5 antibody [2G2] (ab28441) at 1/1000 dilution

Lane 1 : SH-SY5Y cell lysate
Lane 2 : SK-N-SH cell lysate
Lane 3 : Mouse brain tissue


Predicted band size : 33 kDa

Protocols

  • Protocol Booklet

    • References for Anti-Cdk5 antibody [2G2] (ab28441)

    ab28441 has not yet been referenced specifically in any publications.

    Publishing research using ab28441? Please let us know so that we can cite the reference in this datasheet

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"