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Anti-Cdk5 antibody (ab19426)

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Overview

Product name

Anti-Cdk5 antibody
See all Cdk5 products (15) ...

Description

Rabbit polyclonal to Cdk5

Specificity

No reaction was observed against other related cyclin dependent kinases.

Tested applications

WB, ELISAmore details

Cross reactivity

Reacts with

Mouse, Rat, Human

Immunogen

Synthetic peptide (Human) conjugated to KLH (C terminal).

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: 0.01% Sodium Azide

Purity

Whole antiserum

Purification notes

Delipidation and defibrination.

Clonality

Polyclonal

Isotype

IgG

Research areas

Cancer >> Cell cycle >> Cell division
Neuroscience >> Neurology process >> Neurogenesis
Cell Biology >> Cell Cycle >> Kinases/Phosphatases >> Cdks

Applications

Show applications key

Our Abpromise guarantee covers the use of ab19426 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • WB

     

  • ELISA

     

Application notes

ELISA: 1/500 - 1/2000. WB: 1/500. Predicted molecular weight: 35 kDa. Dilution optimised using Chromogenic detection. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.

Target

Function

Probably involved in the control of the cell cycle. Interacts with D1 and D3-type G1 cyclins. Can phosphorylate histone H1, tau, MAP2 and NF-H and NF-M. Also interacts with p35 which activates the kinase.

Sequence similarities

Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
Contains 1 protein kinase domain.

Cellular localization

Cytoplasm. Cell projection > lamellipodium. Cell projection > growth cone. In axonal growth cone with extension to the peripheral lamellipodia.

Target information above from: UniProt accessionQ00535 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • Cdk 5 antibody
  • Cdk5 antibody
  • CDK5_HUMAN antibody
  • Cell division protein kinase 5 antibody
  • Crk6 antibody
  • Cyclin dependent kinase 5 antibody
  • Cyclin-dependent kinase 5 antibody
  • Protein kinase CDK5 splicing antibody
  • PSSALRE antibody
  • Serine threonine protein kinase PSSALRE antibody
  • Serine/threonine-protein kinase PSSALRE antibody
  • Tau protein kinase II catalytic subunit antibody
  • TPKII catalytic subunit antibody
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Database links

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References for Anti-Cdk5 antibody (ab19426)

ab19426 has not yet been referenced specifically in any publications.

Publishing research using ab19426? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"