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Western blot - Cdk7 antibody (ab894)
Western blot - Cdk7 antibody (ab894)
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Cdk7 antibody (ab894)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Cdk7 antibody (ab894)
(enlarge)


Product Name 

Cdk7 antibody

 

See all Cdk7 antibodies (9)...

Product type 

Primary antibodies

Description 

Rabbit polyclonal to Cdk7

Immunogen 

Synthetic peptide conjugated to KLH, corresponding to a region between amino acids 330-346 of Human Cdk7.

Reacts with 
(species key)

Hu

Tested applications 
(see key)

WB


Abreviews 

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(see key)


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Application notes 
(see key)

Recommended dilutions
WB: 1/1000. Detects a band of approximately 36 kDa (predicted molecular weight: 41.5 kDa).

Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Positive control 
(see definition)

NIH3T3 whole cell lysate.

Cellular localization 

Nuclear

Research areas 

Chromatin and Nuclear Signaling >> Cell cycle >> Kinases/Phosphatases >> Cdks
Cell Biology >> Cell Cycle >> Kinases/Phosphatases >> Cdks

Relevance 

Cdk7 is a member of the cyclin dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. Cdk7 forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle.

 

Alternative names Cdk7 antibody (ab894)

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

1022    (Human)

Omim

    

601955    (Human)

SwissProt

    

P50613    (Human)

Raised in 

Rabbit

Clonality 

Polyclonal

Isotype 

IgG

Purity 

Immunogen affinity purified

Storage buffer 

Preservative: None
Constituents: PBS, Sucrose

Form 

Liquid

Concentration 

2.000 mg/ml

Storage instructions 

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

 

At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Cdk7 antibody is on this datasheet. But please do contact us if you would like any reassurance!


See below for Cdk7 antibody images, references, products related to ab894 and other tools.

 

Cdk7 antibody images:

Product image  Western blot - Cdk7 antibody (ab894)

Western blot - Cdk7 antibody (ab894)



Predicted band size : 41.5 kDa


ab894 at 1/1000 dilution staining approximately 36kDa band of mouse cdk7 in NIH3T3 whole cell lysate by Western blot (ECL).

 

Product image  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Cdk7 antibody (ab894)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Cdk7 antibody (ab894)

ab894 staining human epithelial cells of intestinal villus at 4.0 µg/ml by IHC-P.

 
 

Search PubMed (MEDLINE) for references to Cdk7

 

Cdk7 antibody - more information

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