Anti-Cdk9 antibody (ab10874)

Overview

  • Product nameAnti-Cdk9 antibodySee all Cdk9 primary antibodies ...
  • Description
    Rabbit polyclonal to Cdk9
  • Specificityab10874 does not cross react with other cyclin dependent kinases.
  • Tested applicationsELISA, IHC-P, RIA, WB, IHC-Fr, IPmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Full length fusion protein corresponding to human Cdk9.

Properties

Applications

Our Abpromise guarantee covers the use of ab10874 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/500 - 1/2000.
IHC-P 1/200 - 1/1000.
RIA Use at an assay dependent dilution.
WB 1/500 - 1/1000. Predicted molecular weight: 44.6 kDa.
IHC-Fr Use at an assay dependent dilution.
IP Use at an assay dependent dilution.

Target

  • FunctionMember of the cyclin-dependent kinase pair (CDK9/cyclin-T) complex, also called positive transcription elongation factor b (P-TEFb), which facilitates the transition from abortive to production elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAP II), SUPT5H and RDBP. The CDK9/cyclin-K complex has also a kinase activity toward CTD of RNAP II and can substitute for P-TEFb in vitro.
  • Tissue specificityUbiquitous.
  • Sequence similaritiesBelongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
    Contains 1 protein kinase domain.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • C 2k antibody
    • C-2K antibody
    • CDC2 related kinase antibody
    • CDC2L4 antibody
    • Cdk 9 antibody
    • Cdk9 antibody
    • CDK9_HUMAN antibody
    • Cell division cycle 2 like protein kinase 4 antibody
    • Cell division cycle 2-like protein kinase 4 antibody
    • Cell division protein kinase 9 antibody
    • CTK1 antibody
    • Cyclin dependent kinase 9 antibody
    • Cyclin-dependent kinase 9 antibody
    • PITALRE antibody
    • Serine threonine protein kinase PITALRE antibody
    • Serine/threonine-protein kinase PITALRE antibody
    • TAK antibody
    • Tat associated kinase complex catalytic subunit antibody
    see all

References for Anti-Cdk9 antibody (ab10874)

ab10874 has not yet been referenced specifically in any publications.

Product Wall

Thank you very much for your interest in our products.

We have three antibodies which may interest you as they are all tested for both IP and WB.In addition,the homology between the two species is 100% for this protein, therefore,it seems ver...

Read More
Application Western blot
Sample Human Cell lysate - whole cell (peripheral human lymphocytes and thymocytes)
Loading amount 5 µg
Specification peripheral human lymphocytes and thymocytes
Blocking step Milk as blocking agent for 30 minute(s) · Concentration: 4%
Username

Dr. Helen Brown

Verified customer

Submitted Apr 18 2006

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"