Overview

  • Product nameAnti-Cell adhesion molecule 4 antibodySee all Cell adhesion molecule 4 primary antibodies ...
  • Description
    Rabbit polyclonal to Cell adhesion molecule 4
  • Tested applicationsIP, WB, ELISA, IHC-P, ICC/IF more details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide derived from an internal region of human Cell adhesion molecule 4.

  • Positive control
    • A549 cells, extracts from RAW264.7 cells, human brain tissue.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, PBS (without Mg2+ and Ca2+), 150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Clonality Polyclonal
  • IsotypeIgG
  • Research Areas

Applications

Our Abpromise guarantee covers the use of ab69605 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
IP Use at an assay dependent dilution. PubMed: 21482674
WB 1/500 - 1/1000. Detects a band of approximately 48 kDa (predicted molecular weight: 43 kDa).
ELISA 1/20000.
IHC-P 1/50 - 1/100.
ICC/IF 1/500 - 1/1000.

Target

  • FunctionInvolved in the cell-cell adhesion. Has calcium- and magnesium-independent cell-cell adhesion activity. May have tumor-suppressor activity.
  • Tissue specificityExpressed in brain, prostate, brain, kidney and some other organs.
  • Sequence similaritiesBelongs to the nectin family.
    Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • Post-translational
    modifications
    N-glycosylated.
  • Cellular localizationMembrane.
  • Target information above from: UniProt accession Q8NFZ8 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links
  • Alternative names
    • CADM 4 antibody
    • cadm4 antibody
    • CADM4_HUMAN antibody
    • Cell adhesion molecule 4 antibody
    • IGSF4C antibody
    • Immunoglobulin superfamily member 4C antibody
    • Necl 4 antibody
    • NECL-4 antibody
    • NECL4 antibody
    • Nectin like 4 antibody
    • Nectin like protein 4 antibody
    • Nectin-like protein 4 antibody
    • synCAM4 antibody
    • TSLC1 like 2 antibody
    • TSLC1 like protein 2 antibody
    • TSLC1-like protein 2 antibody
    • TSLL2 antibody
    see all

Anti-Cell adhesion molecule 4 antibody images

  • All lanes : Anti-Cell adhesion molecule 4 antibody (ab69605) at 1/500 dilution

    Lane 1 : extracts from RAW264.7 cells
    Lane 2 : extracts from RAW264.7 cells with immunising peptide at 10 µg

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 43 kDa
    Observed band size : 43 kDa
    Additional bands at : 55 kDa. We are unsure as to the identity of these extra bands.
  • A549 cells,stained with ab69605 at 1/500-1/1000 dilution, with and without the immunising peptide.
  • Human brain tissue stained with ab69605 at 1/50-1/100 dilution, with and without the immunising peptide.

References for Anti-Cell adhesion molecule 4 antibody (ab69605)

This product has been referenced in:
  • Jang SM  et al. Clinicopathological significance of CADM4 expression, and its correlation with expression of E-cadherin and Ki-67 in colorectal adenocarcinomas. J Clin Pathol 65:902-6 (2012). IHC-P ; Human . Read more (PubMed: 22718847) »
  • Yang S  et al. Lack of Protein 4.1G Causes Altered Expression and Localization of the Cell Adhesion Molecule Nectin-Like 4 in Testis and Can Cause Male Infertility. Mol Cell Biol 31:2276-86 (2011). IP ; Mouse . Read more (PubMed: 21482674) »

See all 2 Publications for this product

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