Anti-Cell adhesion molecule 4 antibody (ab69605)

Overview

• Product nameAnti-Cell adhesion molecule 4 antibodySee all Cell adhesion molecule 4 primary antibodies ...
• Description
  Rabbit polyclonal to Cell adhesion molecule 4
• Tested applicationsIP, WB, ELISA, IHC-P, ICC/IF more details
• Species reactivity
  Reacts with: Mouse, Rat, Human
  
• Immunogen

  Synthetic peptide derived from an internal region of human Cell adhesion molecule 4.

• Positive controlA549 cells, extracts from RAW264.7 cells, human brain tissue.

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• Storage bufferPreservative: 0.02% Sodium Azide
  Constituents: 50% Glycerol, PBS (without Mg²⁺ and Ca²⁺), 150mM Sodium chloride, pH 7.4
• Concentration information loading...
• PurityImmunogen affinity purified
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Cancer
  • Oncoproteins/suppressors
  • Tumor suppressors
  • Other

Applications

Target

• FunctionInvolved in the cell-cell adhesion. Has calcium- and magnesium-independent cell-cell adhesion activity. May have tumor-suppressor activity.
• Tissue specificityExpressed in brain, prostate, brain, kidney and some other organs.
• Sequence similaritiesBelongs to the nectin family.
  Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
  Contains 1 Ig-like V-type (immunoglobulin-like) domain.
• Post-translational
  modificationsN-glycosylated.
• Cellular localizationMembrane.

Target information above from: UniProt accession Q8NFZ8 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 199731 Human
  • Entrez Gene: 260299 Mouse
  • Entrez Gene: 365216 Rat
  • Omim: 609744 Human
  • SwissProt: Q8NFZ8 Human
  • SwissProt: Q8R464 Mouse
  • SwissProt: Q1WIM1 Rat
  • Unigene: 370984 Human

  • Unigene: 178322 Mouse
  • Unigene: 198138 Rat

  see all

• Alternative names
  CADM 4 antibodycadm4 antibodyCADM4_HUMAN antibody

  Cell adhesion molecule 4 antibodyIGSF4C antibodyImmunoglobulin superfamily member 4C antibodyNecl 4 antibodyNECL-4 antibodyNECL4 antibodyNectin like 4 antibodyNectin like protein 4 antibodyNectin-like protein 4 antibodysynCAM4 antibodyTSLC1 like 2 antibodyTSLC1 like protein 2 antibodyTSLC1-like protein 2 antibodyTSLL2 antibody

  see all

Anti-Cell adhesion molecule 4 antibody images

• 

  Western blot - Cell adhesion molecule 4 antibody (ab69605)
  All lanes : Anti-Cell adhesion molecule 4 antibody (ab69605) at 1/500 dilution
  
  Lane 1 : extracts from RAW264.7 cells
  Lane 2 : extracts from RAW264.7 cells with immunising peptide at 10 µg
  
  Lysates/proteins at 30 µg per lane.
  
  
  Predicted band size : 43 kDa
  Observed band size : 43 kDa
  Additional bands at : 55 kDa. We are unsure as to the identity of these extra bands.
• 

  Immunocytochemistry/ Immunofluorescence - Cell adhesion molecule 4 antibody (ab69605)
  A549 cells,stained with ab69605 at 1/500-1/1000 dilution, with and without the immunising peptide.
• 

  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Cell adhesion molecule 4 antibody (ab69605)
  Human brain tissue stained with ab69605 at 1/50-1/100 dilution, with and without the immunising peptide.