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Product Name
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Cenexin1/ODF2 antibody
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to Cenexin1/ODF2
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Note on antibody grade |
Fast-Track antibodies
- Immunogen affinity purified
- high ELISA titre values
- released early (to accelerate your research)
- 950 Abpoints to the 1st researcher
who submits conclusive data (positive or negative):
Read the Fast-Track antibody Terms of Use
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Immunogen
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Synthetic peptide conjugated to KLH derived from within residues 750 to the C-terminus of Human Cenexin1/ODF2. (Peptide available as ab43839.)
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Predicted to react
(species key)
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Hu, Ms
(Due to sequence homology)
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Abreviews
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Application notes
(see key)
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Recommended dilutions
This antibody gave a positive result in ELISA against the immunizing peptide (ab43839).
Not yet tested in other applications.
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Cellular localization
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Localized to the centrosome
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Research areas
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Cell Biology >> Cell Cycle >> Cell Division >> Spindle
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Relevance
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Cenexin1 is an isoform of the outer dense fiber 2 (ODF2), that unlike ODF2 is present in several cell types tested. Cenexin1 is required for proper localization of Plk1 to the centrosomes. This centrosomal localization of Plk1 is required for proper microtubule function. Cenexin1 recruits Plk1 via a C-terminal extension of cenexin1 that is not present in ODF2. Cenexin1 is required for proper mitotic progression; depletion of hCenexin1 ultimately leads to chromosome missegregation and apoptosis.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Immunogen affinity purified
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Storage buffer
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Preservative: 0.02% Sodium Azide
Constituents: 1% BSA, PBS, pH 7.4 Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Form
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Liquid
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Concentration
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0.500 mg/ml
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Storage instructions
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Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Cenexin1/ODF2 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to Cenexin1/ODF2
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Cenexin1/ODF2 antibody - more information
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Customer reviews (feedback) regarding Cenexin1/ODF2 antibody |
Customer FAQs regarding Cenexin1/ODF2 antibody |
Protocols for Cenexin1/ODF2 antibody |
Price and availability of products related to Cenexin1/ODF2 antibody |
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Cenexin1/ODF2 antibody - related products:
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Cenexin1/ODF2 antibody - other tools:
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Contact Abcam with a Technical Enquiry about Cenexin1/ODF2 antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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