Loading...
You have changed your country from
to
. Please be aware that this will change the currency in the purchasing process.
Products:Epigenetics and Nuclear Signaling >> Chromosome Structure >> Centromeres
Overview
Product name
Cenexin1/ODF2 peptide
See all Cenexin1/ODF2 products (2) ...
Protein description
Synthetic peptide derived from within residues 750 to the C-terminus of Human Cenexin1/ODF2.(Note: the amino acid sequence is proprietary)This peptide was used as an immunogen for ab43840 - Cenexin1/ODF2 antibody.
Protein length
829 amino acids
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Information available upon request.
Concentration
Concentration information loading...
Research areas
Developmental Biology >> Reproduction >> Fertilisation
Cell Biology >> Cell Cycle >> Cell Division >> Centromere
Epigenetics and Nuclear Signaling >> Chromosome Structure >> Centromeres
Applications
Application notes
This peptide can be used with studies using ab43840.
Protein info
Function
Seems to be a major component of sperm tail outer dense fibers (ODF). ODFs are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail. May have a modulating influence on sperm motility. Functions as a general scaffold protein that is specifically localized at the distal/subdistal appendages of mother centrioles. Component of the centrosome matrix required for the localization of PLK1 and NIN to the centrosomes. Required for the formation and/or maintenance of normal CETN1 assembly.
Tissue specificity
Testis-specific (at protein level). Highly expressed in cytoplasm of step 2 round spermatids. Detected in the middle piece and extends to about half the principal piece of the sperm tails.
Sequence similarities
Belongs to the ODF2 family.
Post-translational
modifications
Tyrosine phosphorylated.
Cellular localization
Cytoplasm > cytoskeleton > centrosome. Cell projection > cilium. Cytoplasm > cytoskeleton > centrosome > centriole. Cytoplasm > cytoskeleton > spindle pole. Localized at the microtubule organizing centers in interphase and spindle poles in mitosis. Localized at the distal/subdistal appendages of mother centrioles.
Target information above from: UniProt accessionQ5BJF6
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
References for Cenexin1/ODF2 peptide (ab43839)
ab43839 has not yet been referenced specifically in any publications.
Publishing research using ab43839? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"