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Product Name
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Chd7 antibody
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See all Chd7 antibodies (2)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to Chd7
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Note on antibody grade |
Fast-Track antibodies
- Immunogen affinity purified
- high ELISA titre values
- released early (to accelerate your research)
- 950 Abpoints to the 1st researcher
who submits conclusive data (positive or negative):
Read the Fast-Track antibody Terms of Use
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Immunogen
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Synthetic peptide conjugated to KLH derived from within residues 2950 to the C-terminus of Mouse Chd7. (Peptide available as ab31859.)
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Predicted to react
(species key)
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Ms
(Due to sequence homology)
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Abreviews
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Application notes
(see key)
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Recommended dilutions
This antibody gave a positive result in ELISA against the immunizing peptide (ab31859).
Not yet tested in other applications.
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Cellular localization
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Nuclear
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Research areas
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Chromatin and Nuclear Signaling >> Chromatin Binding Proteins >> Methyl Lysine
Chromatin and Nuclear Signaling >> Chromatin Binding Proteins >> Methyl Arginine
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Relevance
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Human CHD7 is a chromodomain helicase DNA-binding protein and mutations in the CHD7 gene are a major cause of CHARGE syndrome. CHARGE syndrome is a well characterized multiple-malformation syndrome with distinctive diagnostic critera. Anomalies include ocular coloboma, choanal atresia, cranial nerve defects, distinctive external and inner ear abnormalities, hearing loss, cardiovascular malformations, urogenital anomalies, and growth retardation.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Immunogen affinity purified
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Storage buffer
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Preservative: 0.02% Sodium Azide
Constituents: 1% BSA, PBS, pH 7.4 Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Form
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Liquid
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Concentration
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0.500 mg/ml
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Storage instructions
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Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Chd7 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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References for Chd7 antibody (ab31824)
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This product has been used in: (two most recent references)
Schnetz MP et al. Genomic distribution of CHD7 on chromatin tracks H3K4 methylation patterns. Genome Res 19:590-601 (2009). ChIP/Chip; Human. PubMed: 19251738
Layman WS et al. Defects in neural stem cell proliferation and olfaction in Chd7 deficient mice indicate a mechanism for hyposmia in human CHARGE syndrome. Hum Mol Genet 18:1909-23 (2009). IHC-FoFr; Mouse. PubMed: 19279158
If you publish research using ab31824 please let us know so that we can cite the reference on this datasheet.
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Search PubMed (MEDLINE) for references to Chd7
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Chd7 antibody - more information
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Customer reviews (feedback) regarding Chd7 antibody |
Customer FAQs regarding Chd7 antibody |
Protocols for Chd7 antibody |
Price and availability of products related to Chd7 antibody |
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Chd7 antibody - related products:
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Chd7 antibody - other tools:
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Contact Abcam with a Technical Enquiry about Chd7 antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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