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Anti-Chromogranin A antibody [23A1] (ab36997)

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Overview

  • Product nameAnti-Chromogranin A antibody [23A1]See all Chromogranin A primary antibodies ...
  • Description
    Mouse monoclonal [23A1] to Chromogranin A
  • Tested applicationsWB, Sandwich ELISA more details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant human CGA protein purified from E.coli.

  • Positive controlBosc23 cell lysate transfected with myc/His-CGA. Human adrenal gland tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab36997 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
WB WB: 1/2000. Detects a band of approximately 65-78 kDa (predicted molecular weight: 51 kDa).
Sandwich ELISA sELISA: Use a concentration of 1 µg/ml. Can be paired for Sandwich ELISA with Rabbit polyclonal to Chromogranin A (ab17064). For sandwich ELISA, use this antibody as Capture with ab17064 as Detection.

Target

  • FunctionPancreastatin strongly inhibits glucose induced insulin release from the pancreas.
  • Sequence similaritiesBelongs to the chromogranin/secretogranin protein family.
  • Post-translational
    modifications    Sulfated on tyrosine residues and/or contains sulfated glycans.
    O-glycosylated with core 1 or possibly core 8 glycans.
  • Cellular localizationSecreted. Neuroendocrine and endocrine secretory granules.

    • Target information above from: UniProt accession P10645 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links
  • FormAccording to the Swiss-Prot database, this protein has many different forms which correspond to various molecular weights; thus the possible variation from the predicted molecular weight of 51kDa.
    • Alternative names
        beta Granin antibodyCGA antibodyCHG A antibody
        CHGA antibodyChromogranin A parathyroid secretory protein 1 antibodyChromogranin A precursor antibodyChromograninA antibodyCMGA_HUMAN antibodyER-37 antibodyPancreastatin antibodyParastatin antibodyParathyroid secretory protein 1 antibodyPituitary secretory protein I antibodySP I antibodySP-I antibodySP1 antibodySPI antibodyVasostatin antibodyVasostatin I antibodyVasostatin II antibody
      see all

    Anti-Chromogranin A antibody [23A1] images

    Protocols

    References for Anti-Chromogranin A antibody [23A1] (ab36997)

    ab36997 has not yet been referenced specifically in any publications.

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