Anti-Claudin 10 antibody (ab52234)
Key features and details
- Rabbit polyclonal to Claudin 10
- Suitable for: ELISA, WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-Claudin 10 antibody
See all Claudin 10 primary antibodies -
Description
Rabbit polyclonal to Claudin 10 -
Host species
Rabbit -
Tested applications
Suitable for: ELISA, WB, IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse -
Immunogen
Synthetic peptide (Human)
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Positive control
- Extracts from LOVO cells.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab52234 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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ELISA |
Use at an assay dependent concentration.
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WB | (1) |
1/300 - 1/1000. Detects a band of approximately 24 kDa (predicted molecular weight: 24 kDa).
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IHC-P | (1) |
Use at an assay dependent concentration.
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Notes |
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ELISA
Use at an assay dependent concentration. |
WB
1/300 - 1/1000. Detects a band of approximately 24 kDa (predicted molecular weight: 24 kDa). |
IHC-P
Use at an assay dependent concentration. |
Target
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Function
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. -
Sequence similarities
Belongs to the claudin family. -
Cellular localization
Cell junction > tight junction. Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 9071 Human
- Entrez Gene: 58187 Mouse
- SwissProt: P78369 Human
- SwissProt: Q5W075 Human
- SwissProt: Q6IBF9 Human
- SwissProt: Q96N78 Human
- SwissProt: Q8VC62 Mouse
- SwissProt: Q9Z0S6 Mouse
see all -
Alternative names
- Claudin-10 antibody
- Claudin10 antibody
- CLD10_HUMAN antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (5)
ab52234 has been referenced in 5 publications.
- Sebastián I et al. Disassembly of the apical junctional complex during the transmigration of Leptospira interrogans across polarized renal proximal tubule epithelial cells. Cell Microbiol 23:e13343 (2021). PubMed: 33864347
- Gindele JA et al. Intermittent exposure to whole cigarette smoke alters the differentiation of primary small airway epithelial cells in the air-liquid interface culture. Sci Rep 10:6257 (2020). PubMed: 32277131
- Curry JN et al. Combinatorial expression of claudins in the proximal renal tubule and its functional consequences. Am J Physiol Renal Physiol 318:F1138-F1146 (2020). PubMed: 32174144
- Tang J et al. Effects of mesenchymal stem cells on interleukin-1ß-treated chondrocytes and cartilage in a rat osteoarthritic model. Mol Med Rep 12:1753-60 (2015). WB . PubMed: 25892273
- Aschauer L et al. Delineation of the key aspects in the regulation of epithelial monolayer formation. Mol Cell Biol 33:2535-50 (2013). PubMed: 23608536