Clomiphene citrate, Estrogen receptor modulator (SERM) (ab141183)
Key features and details
- Selective estrogen receptor modulator (SERM)
- CAS Number: 50-41-9
- Purity: > 98%
- Soluble in DMSO to 10 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Clomiphene citrate, Estrogen receptor modulator (SERM) -
Description
Selective estrogen receptor modulator (SERM) -
Biological description
Selective estrogen receptor modulator (SERM) (IC50 = 16 μM). Able to regulate apoptosis in tissue and cellular targets of estrogen signaling. Displays antiproliferative effects in vitro. Active in vivo.
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Purity
> 98% -
CAS Number
50-41-9 -
Chemical structure
Properties
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Chemical name
2-[4-(2-Chloro-1,2-diphenylethenyl)phenoxy]-N,N-diethylethanamine citrate -
Molecular weight
598.09 -
Molecular formula
C26H28ClNO.C6H8O7 -
PubChem identifier
60974 -
Storage instructions
Store at +4°C. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 10 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
O=C(O)C(O)(CC(=O)O)CC(=O)O.CCN(CCOc1ccc(cc1)/C(c2ccccc2)=C(/Cl)c3ccccc3)CC -
Source
Synthetic
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Research areas
- Signal Transduction
- Signaling Pathway
- Nuclear Signaling
- Nuclear Hormone Receptors
- Retinoic & Retinoid
- Signal Transduction
- Signaling Pathway
- Nuclear Signaling
- Nuclear Hormone Receptors
- Vitamin D Receptor
- Epigenetics and Nuclear Signaling
- Nuclear Signaling Pathways
- Nuclear Receptors
- Orphan Nuclear Receptors
- Metabolism
- Pathways and Processes
- Metabolic signaling pathways
- Nucleotide metabolism
- Molecular processes
- Mitochondrial transcription
Images
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (1)
ab141183 has been referenced in 1 publication.
- Si L et al. A human-airway-on-a-chip for the rapid identification of candidate antiviral therapeutics and prophylactics. Nat Biomed Eng 5:815-829 (2021). PubMed: 33941899