Anti-Complement C3 antibody (ab117244)

Overview

  • Product nameAnti-Complement C3 antibody
  • Description
    Rabbit polyclonal to Complement C3
  • Tested applicationsELISA more details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Purified Human Complement C3 protein.

Properties

Applications

Our Abpromise guarantee covers the use of ab117244 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
ELISA Use at an assay dependent dilution.

Target

  • RelevanceC3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.
  • Cellular localizationSecreted
  • Database links
  • Alternative names
    • C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1 antibody
    • C3a anaphylatoxin antibody
    • Complement C3 alpha chain antibody
    • Complement C3 antibody
    • Complement C3b alpha' chain antibody
    • Complement C3c alpha' chain fragment 1 antibody
    • Complement C3c alpha' chain fragment 2 antibody
    • Complement C3d fragment antibody
    • Complement C3dg fragment antibody
    • Complement C3f fragment antibody
    • Complement C3g fragment antibody
    • CPAMD1 antibody
    • omplement C3 beta chain antibody
    see all

References for Anti-Complement C3 antibody (ab117244)

ab117244 has not yet been referenced specifically in any publications.

Product Wall

In ELISA (antibody capture assay) the titer for this antibody was determined to be 1:25,000.
The recommended protocol is as follow :


Use 96 well ELISA plates
Apply antigen C3 complement about 100 ng/50 ul per well in PBS. Overnig...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"