(MS109)
Anti-Complex I subunit 8 kDa antibody [17C8E4E11 ] (ab110245)
Overview
- Product nameAnti-Complex I subunit 8 kDa antibody [17C8E4E11 ]
- DescriptionMouse monoclonal [17C8E4E11 ] to Complex I subunit 8 kDa
- Tested applicationsWB more details
- Species reactivityReacts with: Mouse, Rat, Cow, Human
- Immunogen
Bovine Complex I subunit 8 kDa.
- Positive controlIsolated mitochondria from Human, Bovine, Rat and Mouse hearts.
Properties
- FormLiquid
- Storage instructionsStore at +4°C. Do not freeze.
- Storage bufferPreservative: 0.02% Sodium azide
Constituent: HBS -
Concentration information loading... - Purification notesab110245 was produced in vitro using hybridomas grown in serum-free medium, and then purified by biochemical fractionation.
- Clonality Monoclonal
- Clone number17C8E4E11
- IsotypeIgG1
- Light chain typekappa
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Research Areas
Applications
Our Abpromise guarantee covers the use of ab110245 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Notes |
|---|---|
| WB | WB: Use a concentration of 1 µg/ml. |
Target
- RelevanceCore subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
- Cellular localizationMitochondrial
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Database links
- Entrez Gene: 4728 Human
- Entrez Gene: 225887 Mouse
- Entrez Gene: 293652 Rat
- Omim: 602141 Human
- SwissProt: 287027 Cow
- SwissProt: O00217 Human
- SwissProt: Q8K3J1 Mouse
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Alternative names
- BC021616 antibodyCI 23k antibodyCI23KD antibody
- MGC101957 antibodyMGC37950 antibodyMS109 antibodyNADH dehydrogenase (ubiquinone) Fe S protein 8, 23kDa (NADH coenzyme Q reductase) antibodyNADH ubiquinone oxidoreductase 23 kDa subunit antibodyTYKY antibodyTYKY subunit antibody
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Anti-Complex I subunit 8 kDa antibody [17C8E4E11 ] images
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![Western blot - Anti-Complex I subunit 8 kDa antibody [17C8E4E11 ] (ab110245)](http://a.abcam.com/ps/datasheet/images/110/ab110245/Complex-I-subunit-8-kDa-Primary-antibodies-ab110245-1.jpg)
Western blot - Anti-Complex I subunit 8 kDa antibody [17C8E4E11 ] (ab110245)All lanes : Anti-Complex I subunit 8 kDa antibody [17C8E4E11 ] (ab110245) at 1 µg/ml
Lane 1 : Human heart mitochondria at 10 µg
Lane 2 : Bovine heart mitochondria at 4 µg
Lane 3 : Rat heart mitochondria at 10 µg
Lane 4 : Mouse heart mitochondria at 10 µg
References for Anti-Complex I subunit 8 kDa antibody [17C8E4E11 ] (ab110245)
This product has been referenced in:
- Thomas RR et al. Recombinant human mitochondrial transcription factor A stimulates mitochondrial biogenesis and ATP synthesis, improves motor function after MPTP, reduces oxidative stress and increases survival after endotoxin. Mitochondrion 11:108-18 (2011). Read more (PubMed: 20727424) »
- Keeney PM et al. Mitochondrial gene therapy augments mitochondrial physiology in a Parkinson's disease cell model. Hum Gene Ther 20:897-907 (2009). Read more (PubMed: 19374590) »
