Anti-Complex II Immunocapture antibody [4H12BG12AG2] (ab109865)
- Product nameAnti-Complex II Immunocapture antibody [4H12BG12AG2]
- DescriptionMouse monoclonal [4H12BG12AG2] to Complex II Immunocapture
- SpecificityHuman, bovine, mouse
- Tested applicationsWB, IP more details
- Species reactivityReacts with: Mouse, Cow, Human
Bovine Heart Complex II, with traces of Complex III.
- Positive controlBovine heart and Human mitochondria.
- Storage instructionsStore at +4°C. Do not freeze.
- Storage bufferPreservative: 0.02% Sodium azide
- Concentration information loading...
- Purification notesab109865 was produced in vitro using hybridomas grown in serum-free medium, and then purified by biochemical fractionation.
- Clonality Monoclonal
- Clone number4H12BG12AG2
- Light chain typekappa
- Research Areas
Our Abpromise guarantee covers the use of ab109865 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||WB: Use at an assay dependent concentration. PubMed: 21346097|
|IP||IP: Use at 100-1 µg/mg of lysate.|
- RelevanceComplex II is also called succinate ubiquinone oxidoreductase or more commonly succinate dehydrogenase complex. This complex is composed of four nuclear encoded subunits and contains a flavin (FAD), non-heme iron centers and a b-type cytochrome as prosthetic groups. It is both a component of the electron transport chain and an enzyme of the Krebs cycle. Complex II deficiencies are seen in OXPHOS genetic disease and found in a type of cancer called paraganglioma.
- Cellular localizationMitochondrial
Anti-Complex II Immunocapture antibody [4H12BG12AG2] images
Staining of Complex II Lane 1: 0.1 mg Bovine mitochondrial lysate Lane 2: 0.5 mg Human mitochondrial lysate Immunoprecipitated using ab109865 at 100 µg/mg lysate
References for Anti-Complex II Immunocapture antibody [4H12BG12AG2] (ab109865)
This product has been referenced in:
- Mendez-Figueroa H et al. Effects of Labor on Placental Fatty Acid Beta Oxidation. J Matern Fetal Neonatal Med : (2012). Human . Read more (PubMed: 22928498) »
- Abdelmegeed MA et al. PPARalpha expression protects male mice from high fat-induced nonalcoholic fatty liver. J Nutr 141:603-10 (2011). WB ; Mouse . Read more (PubMed: 21346097) »