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MitoSciences (MS201c)

Anti-Complex II Immunocapture antibody [4H12BG12AG2] (ab109865)

Submit an Abreview Q&A (1)Specific References (6)

Overview

  • Product nameAnti-Complex II Immunocapture antibody [4H12BG12AG2]
  • Description
    Mouse monoclonal [4H12BG12AG2] to Complex II Immunocapture
  • SpecificityHuman, bovine, mouse
  • Tested applicationsWB, IP more details
  • Species reactivity
    Reacts with: Mouse, Cow, Human
  • Immunogen

    Bovine Heart Complex II, with traces of Complex III.

  • Positive controlBovine heart and Human mitochondria.

Properties

Applications

Our Abpromise guarantee covers the use of ab109865 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
WB WB: Use at an assay dependent concentration. PubMed: 21346097
IP IP: Use at 100-1 µg/mg of lysate.

Target

  • RelevanceComplex II is also called succinate ubiquinone oxidoreductase or more commonly succinate dehydrogenase complex. This complex is composed of four nuclear encoded subunits and contains a flavin (FAD), non-heme iron centers and a b-type cytochrome as prosthetic groups. It is both a component of the electron transport chain and an enzyme of the Krebs cycle. Complex II deficiencies are seen in OXPHOS genetic disease and found in a type of cancer called paraganglioma.
  • Cellular localizationMitochondrial

Anti-Complex II Immunocapture antibody [4H12BG12AG2] images

  • Immunoprecipitation - Complex II Immunocapture antibody [4H12BG12AG2] (ab109865)
    Immunoprecipitation - Complex II Immunocapture antibody [4H12BG12AG2] (ab109865)
    Staining of Complex II Lane 1: 0.1 mg Bovine mitochondrial lysate Lane 2: 0.5 mg Human mitochondrial lysate Immunoprecipitated using ab109865 at 100 µg/mg lysate

References for Anti-Complex II Immunocapture antibody [4H12BG12AG2] (ab109865)

This product has been referenced in:
  • Mendez-Figueroa H  et al. Effects of Labor on Placental Fatty Acid Beta Oxidation. J Matern Fetal Neonatal Med : (2012). Human . Read more (PubMed: 22928498) »
  • Abdelmegeed MA  et al. PPARalpha expression protects male mice from high fat-induced nonalcoholic fatty liver. J Nutr 141:603-10 (2011). WB ; Mouse . Read more (PubMed: 21346097) »

See all 6 Publications for this product

Publishing research using ab109865 ? Please let us know so that we can cite the reference in this datasheet

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Votes: Highest First

Dear technical team, Hope this e-mail finds you well! Kindly advise the suitable antibodies for below specificities as desired by one of our customer : Target :  Mitochondrial Complex I (encoded by mitochondrial DNA & not nuclear DNA)               Mitoch...

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Thank you for contacting us. Please click these links to find the suitable antibodies. Type the MS code in Abcam search box to get the Abcam catalogue number. Complex I http://www.mitosciences.com/complex_i.html Complex IV http://www.mitos...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"