You have changed your country from  to  . Please be aware that this will change the currency in the purchasing process.

Related products

Reassurance, Refunds & Replacements

If your product does not perform as described on this datasheet, we will refund or replace your product...

Read our guarantee »
 

Anti-Constitutive androstane receptor antibody (ab55907)

CodeSizePriceAbpointsAvailability
    
Add to basket
 
  • -
  •   
  •   
  •   
  •  
  •   
  •   
Updating...

Overview

Product name

Anti-Constitutive androstane receptor antibody
See all Constitutive androstane receptor products (6) ...

Description

Rabbit polyclonal to Constitutive androstane receptor

Tested applications

WB, ELISAmore details

Cross reactivity

Reacts with

Recombinant Fragment

Predicted to work with

Mouse, Rat

Immunogen

Synthetic peptide corresponding to N-terminal residues of mouse Constitutive androstane receptor

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Storage buffer

Preservative: 0.01% Sodium Azide
Constituents: 50% Glycerol, PBS

Concentration

Concentration information loading...

Purity

Immunogen affinity purified

Clonality

Polyclonal

Isotype

IgG

Research areas

Signal Transduction >> Metabolism >> Drug metabolism
Epigenetics and Nuclear Signaling >> Nuclear Signaling Pathways >> Nuclear Receptors >> Orphan Nuclear Receptors
Epigenetics and Nuclear Signaling >> Nuclear Signaling Pathways >> Nuclear Receptors >> Retinoic & Retinoid

Applications

Show applications key

Our Abpromise guarantee covers the use of ab55907 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • ShowHide

    WB

     WB: Use a concentration ...Read more →

    WB: Use a concentration of 1 µg/mlPredicted molecular weight: 40 kDa.(for 2 hours. This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein.)

  • ShowHide

    ELISA

     ELISA: Use at an assay d...Read more →

    ELISA: Use at an assay dependent dilution.

Target

Relevance

Constitutive androstane receptor (CAR) is a member of orphan receptor. CAR is mainly expressed in liver and lower levels of expression are observed in heart, muscles, kidney and lung. CYP3A and CYP2B are regulated by CAR, which suggest xenobiotics can activate multiple CYP genes through this receptor. Mouse homolog is induced by phenobarbital and CAR-null mouse demonstrate resistance to acetaminophen toxicity. CAR affects metabolism of drugs and other xenobiotics.

Cellular localization

Nucleus (By similarity)

Alternative names

  • CAR antibody
  • CAR BETA antibody
  • CAR1 antibody
  • CARA antibody
  • Constitutive activator of retinoid response antibody
  • Constitutive active response antibody
  • MGC97144 antibody
  • NR1I3 antibody
  • Nuclear receptor subfamily 1 group I member 3 antibody
  • Orphan nuclear receptor MB67 antibody
  • Orphan nuclear receptor NR1I3 antibody
see all

Database links

References for Anti-Constitutive androstane receptor antibody (ab55907)

ab55907 has not yet been referenced specifically in any publications.

Publishing research using ab55907? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"